호모 사피엔스 종의 단백질 코드 유전자
크로모박스 단백질 호몰로그 3은 인간의 [5] [6] CBX3 유전자에 의해 암호화되는 단백질 이다.
핵외피에서 핵적층 및 헤테로크로마틴 은 내부핵막 에 인접해 있다. 이 유전자에 의해 암호화된 단백질은 DNA와 결합하고 헤테로크로마틴의 구성요소이다. 이 단백질은 또한 내부 핵막에서 발견되는 일체형 막 단백질인 라민 B 수용체와 결합할 수 있습니다. 암호화된 단백질의 이중 결합 기능은 헤테로크로마틴과 내부 핵막의 연관성을 설명할 수 있다. 이 [6]
상호 작용 CBX3는 PIM1 ,[7] Ki-67 ,[8] Lamin B 수용체 ,[9] CBX5 [10] [10] CBX1 과 상호작용하는 것 으로 나타났다.
「 」를 참조해 주세요. 레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000122565 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000029836 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ye Q, Worman HJ (August 1996). "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1" . J Biol Chem . 271 (25): 14653–6. doi :10.1074/jbc.271.25.14653 PMID 8663349 . ^ a b "Entrez Gene: CBX3 chromobox homolog 3 (HP1 gamma homolog, Drosophila)" .^ Koike, N; Maita H; Taira T; Ariga H; Iguchi-Ariga S M (February 2000). "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)" . 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외부 링크 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY
