호모 사피엔스 종의 단백질 코드 유전자
POU 도메인, 클래스 3, 전사 인자 1(일명 Oct-6 )은 사람에게서 POU3F1 [3] [4] 유전자 에 의해 암호화되는 단백질 이다.
「 」를 참조해 주세요. 레퍼런스
추가 정보 Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G (Sep 1990). "Expression and activity of the POU transcription factor SCIP". Science . 249 (4974): 1300–3. Bibcode :1990Sci...249.1300M . doi :10.1126/science.1975954 . PMID 1975954 . Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR (Nov 1990). "Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain" . The EMBO Journal . 9 (11): 3723–32. doi :10.1002/j.1460-2075.1990.tb07585.x . PMC 552128 . PMID 1976514 . Zwilling S, König H, Wirth T (Mar 1995). "High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors" . The EMBO Journal . 14 (6): 1198–208. doi :10.1002/j.1460-2075.1995.tb07103.x . PMC 398197 . PMID 7720710 . Leger H, Sock E, Renner K, Grummt F, Wegner M (Jul 1995). "Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y" . Molecular and Cellular Biology . 15 (7): 3738–47. doi :10.1128/mcb.15.7.3738 . PMC 230612 . PMID 7791781 . Faus I, Hsu HJ, Fuchs E (May 1994). "Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia" . Molecular and Cellular Biology . 14 (5): 3263–75. doi :10.1128/mcb.14.5.3263 . PMC 358693 . PMID 7909356 . Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E (Oct 1995). "Expression of transcription regulating genes in human preimplantation embryos". Human Reproduction . 10 (10): 2787–92. doi :10.1093/oxfordjournals.humrep.a135792 . PMID 8567814 . Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D (Jul 1996). "The POU factor Oct-6 and Schwann cell differentiation". Science . 273 (5274): 507–10. Bibcode :1996Sci...273..507J . doi :10.1126/science.273.5274.507 . PMID 8662541 . S2CID 39349653 . Sock E, Enderich J, Rosenfeld MG, Wegner M (Jul 1996). "Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6" . The Journal of Biological Chemistry . 271 (29): 17512–8. doi :10.1074/jbc.271.29.17512 . PMID 8663425 . Malik KF, Jaffe H, Brady J, Young WS (Apr 1997). "The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U" . Brain Research. Molecular Brain Research . 45 (1): 99–107. doi :10.1016/S0169-328X(96)00238-0 . PMID 9105675 . Sumiyama K, Washio-Watanabe K, Ono T, Yoshida MC, Hayakawa T, Ueda S (Feb 1998). "Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2". Mammalian Genome . 9 (2): 180–1. doi :10.1007/s003359900721 . PMID 9457692 . S2CID 9495282 . Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS (Oct 1998). "Promyelinating Schwann cells express Tst-1/SCIP/Oct-6" . The Journal of Neuroscience . 18 (19): 7891–902. doi :10.1523/JNEUROSCI.18-19-07891.1998 . PMC 6792991 . PMID 9742157 . Kawasaki T, Oka N, Tachibana H, Akiguchi I, Shibasaki H (Mar 2003). "Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies". Acta Neuropathologica . 105 (3): 203–8. doi :10.1007/s00401-002-0630-9 . hdl :2433/148771 . PMID 12557005 . S2CID 2340303 . Beck IM, Müller M, Mentlein R, Sadowski T, Mueller MS, Paus R, Sedlacek R (May 2007). "Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation" . The Journal of Investigative Dermatology . 127 (5): 1107–14. doi :10.1038/sj.jid.5700674 . PMID 17195013 . Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J (Oct 2007). "Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss" . The Journal of Neuroscience . 27 (43): 11552–9. doi :10.1523/JNEUROSCI.5497-06.2007 . PMC 6673231 . PMID 17959798 . 외부 링크 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY