호모 사피엔스 종의 단백질 코드 유전자
NFIA 식별자 에일리어스 NFIA 외부 ID OMIM : 600727 MGI : 108056 HomoloGene : 4086 GenCard : NFIA 유전자 존재론 분자 함수 GO:0001131, GO:000115, GO:0001130, GO:0001204 DNA결합전사인자액티비티 GO:0000980 RNA중합효소II 시스조절영역배열특이적 DNA결합 DNA결합 GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA결합전사활성화제, RNA중합효소II 특이적 전사 인자 결합 크로마틴 결합 GO:0001948 단백질 결합 GO:0001200, GO:0001133, GO:0001201 DNA결합전사인자활성, RNA중합효소II 특이적 셀룰러 컴포넌트 생물학적 과정 출처: 아미고 / QuickGO
맞춤법 종. 인간 마우스 엔트레즈 앙상블 유니프로트 RefSeq(mRNA) RefSeq(단백질) 장소(UCSC) Chr 1 : 60.87 ~61.46 Mb Chr 4: 97.66 ~98.01 Mb PubMed 검색[3] [4] 위키데이터
핵인자 1 A형 은 NFIA [5] [6] 유전자 에 의해 인간 에서 암호화 되는 단백질 이다.
기능. 핵인자 I(NFI) 단백질은 유사하고 아마도 동일한 DNA 결합 특이성을 가진 이합체 DNA 결합 단백질군을 구성한다. 그것들은 세포전사인자 및 아데노바이러스 DNA 복제 를 위한 복제인자로 기능한다. 이 단백질 패밀리의 다양성은 다중 유전자 , 차등 스플라이싱 및 헤테로다이머화에 의해 생성된다. [OMIM [6]
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000162599 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000028565 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Qian F, Kruse U, Lichter P, Sippel AE (July 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics . 28 (1): 66–73. doi :10.1006/geno.1995.1107 . PMID 7590749 . ^ a b "Entrez Gene: NFIA nuclear factor I/A" .
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(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY
