ERF(유전자)

ERF
식별자
에일리어스	ERF, CRS4, PE-2, PE2, ETS2 리프레서 팩터, CHYTS
외부 ID	OMIM : 611888 MGI : 109637 HomoloGene : 68516 GenCard : ERF
유전자 위치(인간)
크르.	19번 염색체(인간)
끝.	42,255,128 bp
유전자 위치(마우스)
크르.	7번 염색체(쥐)
끝.	25,250,761 bp
RNA발현패턴
	상단 표시 위치:
	우측 자궁관; ; 위점막; ; 담낭; ; 좌측 자궁관; ; 뇌하수체 전엽; ; 경골 신경; ; 상부 신경; ; 간우엽; ; 갑상선 좌엽; ; 자궁경관;
	상단 표시 위치:
	노른자낭; ; 입술; ; 상전두회; ; 거울; ; 각막 간질; ; 암요도; ; 적란 세포; ; 장피질; ; 어금니; ; 간좌엽;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	DNA결합전사인자활성; DNA결합; 전사 코어프레서 활성; DNA결합전사억제제활성, RNA중합효소II 특이적; 배열특이적 DNA결합; DNA결합전사인자활성, RNA중합효소II 특이적;
셀룰러 컴포넌트	핵; 핵소체; 세포;
생물학적 과정	세포 분화; 전사조절, DNA템플릿화; 전사, DNA 템플릿; RNA중합효소II에 의한 전사 음성 조절; 유사분열세포주기; RNA중합효소II에 의한 전사조절;
	출처:아미고 / QuickGO
맞춤법
	2077
	13875
	ENSG00000105722
	ENSMUSG000040857
	P50548
	P70459
	NM_001301035; NM_001308402; NM_001312656; NM_006494
	NM_010155
	NP_001287964; NP_001295331; NP_001299585; NP_006485
	NP_034285
	위키데이터
인간 보기/편집	마우스 표시/편집

ETS 도메인을 포함한 전사인자 ERF는 인간의 ERF ^[5]^[6]^[7]유전자에 의해 암호화되는 단백질이다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000105722 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000040857 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ (October 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". The EMBO Journal. 14 (19): 4781–93. doi:10.1002/j.1460-2075.1995.tb00160.x. PMC 394576. PMID 7588608.
^ de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (June 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.
^ "Entrez Gene: ERF Ets2 repressor factor".

추가 정보

Liu D, Pavlopoulos E, Modi W, Moschonas N, Mavrothalassitis G (March 1997). "ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes". Oncogene. 14 (12): 1445–51. doi:10.1038/sj.onc.1200965. PMID 9136988.
Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G (June 1999). "Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation". Molecular and Cellular Biology. 19 (6): 4121–33. doi:10.1128/mcb.19.6.4121. PMC 104371. PMID 10330152.
Dintilhac A, Bernués J (March 2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences". The Journal of Biological Chemistry. 277 (9): 7021–8. doi:10.1074/jbc.M108417200. PMID 11748221.
Dubois T, Howell S, Zemlickova E, Aitken A (April 2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Letters. 517 (1–3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430. S2CID 84792445.
Bain M, Mendelson M, Sinclair J (January 2003). "Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells". The Journal of General Virology. 84 (Pt 1): 41–9. doi:10.1099/vir.0.18633-0. PMID 12533699.
Xiao X, Athanasiou M, Sidorov IA, Horikawa I, Cremona G, Blair D, Barret JC, Dimitrov DS (December 2003). "Role of Ets/Id proteins for telomerase regulation in human cancer cells". Experimental and Molecular Pathology. 75 (3): 238–47. doi:10.1016/S0014-4800(03)00092-3. PMID 14611815.
Wolvetang EJ, Bradfield OM, Hatzistavrou T, Crack PJ, Busciglio J, Kola I, Hertzog PJ (December 2003). "Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis". Neurobiology of Disease. 14 (3): 349–56. doi:10.1016/S0969-9961(03)00107-4. PMID 14678752. S2CID 30142532.
Le Gallic L, Virgilio L, Cohen P, Biteau B, Mavrothalassitis G (February 2004). "ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression". Molecular and Cellular Biology. 24 (3): 1206–18. doi:10.1128/MCB.24.3.1206-1218.2004. PMC 321421. PMID 14729966.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK (July 2007). "Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS". Cell Cycle. 6 (13): 1594–604. doi:10.4161/cc.6.13.4336. PMID 17525531.
Verykokakis M, Papadaki C, Vorgia E, Le Gallic L, Mavrothalassitis G (October 2007). "The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression". The Journal of Biological Chemistry. 282 (41): 30285–94. doi:10.1074/jbc.M704428200. PMID 17699159.

외부 링크

ERF+단백질+미국 국립의학도서관의 의학 주제 제목(MeSH)

이 기사에는 미국 국립 의학 도서관(미국 국립 의학 도서관)의 공공 도메인 텍스트가 포함되어 있습니다.

인간 염색체 19번 유전자에 대한 이 기사는 짧은 글이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000105722 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000040857 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7588608-5] Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ (October 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". The EMBO Journal. 14 (19): 4781–93. doi:10.1002/j.1460-2075.1995.tb00160.x. PMC 394576. PMID 7588608.

[pmid9192842-6] Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (June 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.

[entrez-7] "Entrez Gene: ERF Ets2 repressor factor".

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ERF(유전자)

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