일반전사인자 3C 폴리펩타이드 2는 GTF3C2 [5] [6] 유전자에 의해 인체 내에서 암호화되는 단백질 이다.
상호 작용 GTF3C2는 GTF3C4 [7] 및 GTF3C5 와 [8] 상호 작용하는 것 으로 나타났습니다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000115207 - 앙상블 , 2017년 5월 ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG00000106864 - 앙상블 , 2017년 5월 ^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ Sinn E, Wang Z, Kovelman R, Roeder RG (Jun 1995). "Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors" . Genes Dev . 9 (6): 675–85. doi :10.1101/gad.9.6.675 . PMID 7729686 . ^ "Entrez Gene: GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa" . ^ Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity" . Mol. Cell. Biol . 19 (11): 7697–704. doi :10.1128/mcb.19.11.7697 . PMC 84812 . PMID 10523658 . ^ Hsieh YJ, Wang Z, Kovelman R, Roeder RG (Jul 1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III" . Mol. Cell. Biol . 19 (7): 4944–52. doi :10.1128/mcb.19.7.4944 . PMC 84305 . PMID 10373544 .
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The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)" . DNA Res . 1 (1): 47–56. doi :10.1093/dnares/1.1.47 . PMID 7584028 . Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 . PMID 9110174 . Chu WM, Wang Z, Roeder RG, Schmid CW (1997). "RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2" . J. Biol. Chem . 272 (23): 14755–61. doi :10.1074/jbc.272.23.14755 . PMID 9169441 . Oettel S, Härtel F, Kober I, Iben S, Seifart KH (1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes" . Nucleic Acids Res . 25 (12): 2440–7. doi :10.1093/nar/25.12.2440 . PMC 146769 . PMID 9171097 . Wang Z, Roeder RG (1998). "DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III" . Mol. Cell . 1 (5): 749–57. doi :10.1016/S1097-2765(00)80074-X . PMID 9660958 . Hsieh YJ, Wang Z, Kovelman R, Roeder RG (1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III" . Mol. Cell. Biol . 19 (7): 4944–52. doi :10.1128/mcb.19.7.4944 . PMC 84305 . PMID 10373544 . Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity" . Mol. Cell. Biol . 19 (11): 7697–704. doi :10.1128/mcb.19.11.7697 . PMC 84812 . PMID 10523658 . Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions" . Genome Res . 14 (9): 1711–8. doi :10.1101/gr.2435604 . PMC 515316 . PMID 15342556 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY , Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Innes F, Ramsbottom B, White RJ (2006). "A test of the model that RNA polymerase III transcription is regulated by selective induction of the 110 kDa subunit of TFIIIC" . Nucleic Acids Res . 34 (11): 3399–407. doi :10.1093/nar/gkl432 . PMC 1488882 . PMID 16822860 . Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . S2CID 7827573 . Dumay-Odelot H, Marck C, Durrieu-Gaillard S, Lefebvre O, Jourdain S, Prochazkova M, Pflieger A, Teichmann M (2007). "Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC" . J. Biol. Chem . 282 (23): 17179–89. doi :10.1074/jbc.M611542200 . PMID 17409385 . 외부 링크 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
(1) 기본 도메인
(1.1 ) 베이직 류신 지퍼(bZIP )(1.2) 기본나선-루프-나선 (bHLH )
그룹 A 그룹 B 그룹 C bHLH-PAS 그룹 D 그룹 E 그룹 F bHLH-COE
(1.3) bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) 기본나선경간나선(bHSH)
(2.1) 핵수용체 (CYS4 )
서브패밀리 1 서브패밀리 2 서브 패밀리 3 서브패밀리 4 서브패밀리 5 서브패밀리 6 서브패밀리 0
(2.2) 기타 CY4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) 교대 조성 (2.6) WRKY