폴리오바이러스수용체관련2
Poliovirus receptor-related 2폴리오바이러스 수용체 관련 2(PVRL2)는 사람 혈장막 당단백질이다.[5]
기능.
이 유전자는 Ig-like C2-type 도메인과 Ig-like V-type 도메인으로 단일 패스형 I막 당단백질을 코드한다.이 단백질은 아데렌 접합부의 혈장막 성분 중 하나이다.그것은 또한 단순 헤르페스 바이러스 및 가성포진 바이러스의 특정 돌연변이 변종의 진입로 역할을 하며, 이러한 바이러스의 세포간 확산에 관여한다.이 유전자의 변화는 다발성 경화증의 심각도의 차이와 관련이 있다.다른 Isoform을 인코딩하는 대체 전사 스플라이스 변형이 [5]특징지어졌습니다.
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레퍼런스
- ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000130202 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000062300 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)".
추가 정보
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