NCR2
NCR2NCR2 | |||||||||||||||||||||||||
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식별자 | |||||||||||||||||||||||||
별칭 | NCR2, CD336, LY95, NK-p44, NKP44, dJ149M18.1, 자연 세포독성 트리거 수신기 2 | ||||||||||||||||||||||||
외부 ID | OMIM: 604531 호몰로진: 130365 GeneCard: NCR2 | ||||||||||||||||||||||||
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직교체 | |||||||||||||||||||||||||
종 | 인간 | 마우스 | |||||||||||||||||||||||
엔트레스 |
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앙상블 |
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유니프로트 |
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RefSeq(mRNA) |
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RefSeq(단백질) |
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위치(UCSC) | Chr 6: 41.34 – 41.35Mb | n/a | |||||||||||||||||||||||
PubMed 검색 | [2] | n/a | |||||||||||||||||||||||
위키다타 | |||||||||||||||||||||||||
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천연 세포독성 유발 수용체 2는 인간에서 NCR2 유전자에 의해 암호화된 단백질이다.[3][4]NCR2는 CD336(분화 336 클러스터), NKP44, NKP44, NK-p44, LY95, dJ149M18.1로도 지정되었다.[5]
참조
- ^ a b c GRCh38: 앙상블 릴리스 89: ENSG000096264 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Cantoni C, Bottino C, Vitale M, Pessino A, Augugliaro R, Malaspina A, Parolini S, Moretta L, Moretta A, Biassoni R (Jun 1999). "NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily". J Exp Med. 189 (5): 787–96. doi:10.1084/jem.189.5.787. PMC 2192947. PMID 10049942.
- ^ "Entrez Gene: NCR2 natural cytotoxicity triggering receptor 2".
- ^ "NCR2 natural cytotoxicity triggering receptor 2 [Homo sapiens (human)] - Gene - NCBI".
추가 읽기
- Hershkovitz O, Jivov S, Bloushtain N, et al. (2007). "Characterization of the recognition of tumor cells by the natural cytotoxicity receptor, NKp44". Biochemistry. 46 (25): 7426–36. doi:10.1021/bi7000455. PMID 17536787.
- Forte P, Lilienfeld BG, Baumann BC, Seebach JD (2005). "Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D". J. Immunol. 175 (8): 5463–70. doi:10.4049/jimmunol.175.8.5463. PMID 16210654.
- Fuchs A, Cella M, Kondo T, Colonna M (2005). "Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44". Blood. 106 (6): 2076–82. doi:10.1182/blood-2004-12-4802. PMID 15941912.
- Poggi A, Massaro AM, Negrini S, et al. (2005). "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors". J. Immunol. 174 (5): 2653–60. doi:10.4049/jimmunol.174.5.2653. PMID 15728472.
- Nowbakht P, Ionescu MC, Rohner A, et al. (2005). "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias". Blood. 105 (9): 3615–22. doi:10.1182/blood-2004-07-2585. PMID 15657183.
- Campbell KS, Yusa S, Kikuchi-Maki A, Catina TL (2004). "NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence". J. Immunol. 172 (2): 899–906. doi:10.4049/jimmunol.172.2.899. PMID 14707061.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
- Cantoni C, Ponassi M, Biassoni R, et al. (2004). "The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity". Structure. 11 (6): 725–34. doi:10.1016/S0969-2126(03)00095-9. PMID 12791260.
- Augugliaro R, Parolini S, Castriconi R, et al. (2003). "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells". Eur. J. Immunol. 33 (5): 1235–41. doi:10.1002/eji.200323896. PMID 12731048. S2CID 10724743.
- Allcock RJ, Barrow AD, Forbes S, et al. (2003). "The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44". Eur. J. Immunol. 33 (2): 567–77. doi:10.1002/immu.200310033. PMID 12645956. S2CID 27147251.
- Cantoni C, Ponassi M, Biassoni R, et al. (2003). "Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44". Acta Crystallogr. D. 58 (Pt 10 Pt 2): 1843–5. doi:10.1107/S0907444902012325. PMID 12351833.
외부 링크
- NCR2+단백질,+인간(MesH) 미국 국립 의학 도서관의 의학 과목 제목(MesH)
- PDBe-KB는 인간 자연 세포독성 트리거링 수용체 2(NCR2)에 대해 PDB에서 사용할 수 있는 모든 구조 정보의 개요를 제공한다.