아자타딘

Azatadine
아자타딘
Azatadine.svg
임상 데이터
상호옵티마인
AHFS/Drugs.comMicromedex 상세 소비자 정보
ATC 코드
식별자
  • 11-(1-메틸피페리딘-4-일리덴)-6,11-디히드로-5H-벤조[5,6]시클로헵타[1,2-b]피리딘
CAS 번호
PubChem CID
IUPHAR/BPS
드러그뱅크
켐스파이더
유니
케그
체비
첸블
CompTox 대시보드 (EPA )
화학 및 물리 데이터
공식C20H22N2
몰 질량290.199g/140−1
3D 모델(JSmol)
  • n4c3\C(=C1/CCN(C)CC1)c2cc2CCC3cc4
  • InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-20(17)19/h2-7,12H,8-13,14H2 checkY,
  • 키: SEBMTIQKRHYNIT-UHFFFAOYSA-N
(표준)

아자타딘(Optimine)은 1973년 [1][2]셰링플라우가 출시한 1세대 항히스타민제항콜린제다.

1967년에 [3]특허를 받았습니다.그것은 로라타딘데슬라타딘 [4]: 53 둘 다에 의해 계승되었다.마케팅 승인이 광범위하게 [5][6][7][8]: 290 [9]철회되었습니다.

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레퍼런스

  1. ^ Katelaris C (December 1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology. 8 (2): 103–7. PMID 1982614.
  2. ^ Small P, Barrett D, Biskin N (February 1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of Allergy. 64 (2 Pt 1): 129–31. PMID 1968324.
  3. ^ US 3326924, Villani FJ, Caldwell W, "Azatadine", 1967년 발행
  4. ^ Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". In Pawankar R, Holgate ST, Rosenwasser LJ (eds.). Allergy Frontiers:Therapy and Prevention. Allergy Frontiers. Vol. 5. Springer Science & Business Media. ISBN 9784431993629.
  5. ^ "Azatadine". Drugs.com.
  6. ^ Food and Drug Administration (2005). "Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications". Federal Register 70 FR 10651.
  7. ^ Food and Drug Administration (2007). "Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions". Federal Register 72 FR 8184.
  8. ^ "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF). Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005.
  9. ^ "OGD Suitability Tracking Report (Sorted by Drug Name)". FDA.