2-메틸-5-히드록시트리프타민

2-Methyl-5-hydroxytryptamine
2-메틸-5-히드록시트리프타민
2-Methyl-5-hydroxytryptamine.png
2-Methyl-5-hydroxytryptamine - 2.png
식별자
  • 3-(2-아미노에틸)-2-메틸-1H-인돌-5-올
CAS 번호
펍켐 CID
IUPHAR/BPS
켐스파이더
케그
체비
켐벨
CompTox 대시보드 (EPA)
ECHA InfoCard100.231.402 Edit this at Wikidata
화학 및 물리적 데이터
공식C11H14N2O
어금질량190.246 g·190−1
3D 모델(JSmol)
  • Oc1cc2c(cc1)[nH]c(c2CCN)c
  • InChi=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,13-14H,4-5,12H2,1H3 checkY
  • 키:WYWNEDARFVJQSG-UHFFFAOYSA-N
☒NcheckY (이게 뭐야?) (iii)

2-메틸-5-하이드록시트리프타민(2-메틸세로토닌, 2-메틸-5-HT)은 신경전달물질 세로토닌과 밀접한 관련이 있는 트립타민 유도체로 5-HT3 수용체에서 적당히 선택적인 완전작용제 역할을 한다.[1][2][3]

참고 항목

참조

  1. ^ Elz S, Zimmermann H, Rehse K (1993). "Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines". Archiv der Pharmazie. 326 (11): 893–899. doi:10.1002/ardp.19933261110. PMID 8274071. S2CID 1671270.
  2. ^ Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE (1990). "5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum". Naunyn Schmiedebergs Arch Pharmacol. 342 (1): 9–16. doi:10.1007/bf00178965. PMID 2402303. S2CID 24743785.
  3. ^ Glennon RA, Dukat M, Westkaemper RB (2000-01-01). "Serotonin Receptor Subtypes and Ligands". American College of Neurophyscopharmacology. Archived from the original on 21 April 2008. Retrieved 2008-04-11.


Stub icon

신경계통에 관한 이 약물 기사는 단조롭다. 위키피디아를 확장하여 도울 수 있다.