개연성 G단백 결합 수용체 133 은 인간에서 GPR133 유전자 에 의해 암호화된 단백질 이다.[5] [6]
이 유전자는 접착-GPCR 수용체 집단의 구성원을 인코딩한다. 패밀리 멤버는 GPCR-자극성분해(Gain) 도메인으로 알려진 도메인을 통해 TM7 도메인에 연결된 가변 개수의 단백질 도메인을 가진 세포외 영역을 확장한 것이 특징이다.[7] [8]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000111452 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000044017 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: GPR133 G protein-coupled receptor 133" .^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions" . FEBS Lett . 531 (3): 407–14. doi :10.1016/S0014-5793(02)03574-3 PMID 12435584 . S2CID 7449692 . ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology) . Berlin: Springer. ISBN 978-1-4419-7912-4 ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis" . EMBO J . 31 (6): 1364–78. doi :10.1038/emboj.2012.26 . PMC 3321182 PMID 22333914 . 추가 읽기 Vanti WB, Nguyen T, Cheng R, et al. (2003). "Novel human G-protein-coupled receptors". Biochem. Biophys. Res. Commun . 305 (1): 67–71. doi :10.1016/S0006-291X(03)00709-5 . PMID 12732197 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics . 84 (1): 23–33. doi :10.1016/j.ygeno.2003.12.004 . PMID 15203201 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 .
