응고 인자 II(트롬빈) 수용체 유사 3 으로도 알려진 프로테아제 활성 수용체 4 (PAR-4 )는 인간에서 F2RL3 유전자 에 의해 인코딩 되는 단백질이다.[5]
함수 응고 인자 II(트롬빈) 수용체 유사 3(F2RL3)은 구아노신-뉴클레오티드 결합 단백질과 결합하는 7-트랜섬브레인 영역 수용체 대가족의 일원이다. F2RL3 역시 프로테아제 활성 수용체 계열의 일원이다. F2RL3는 세포외 아미노 종단부 의 단백질 분해에 의해 활성화된다. 새로운 아미노 터미네이터는 테더링 리간드로 기능하며 수용체를 활성화시킨다. F2RL3는 트롬빈 과 트립신 에 의해 활성화된다.[5]
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