리보솜 단백질 S6키나제 알파-2 는 인간에게 RPS6KA2 유전자에 의해 암호화 된 효소 다.[5] [6]
이 유전자는 세린과 트레오닌 키나아제 의 RSK(리보솜 S6 kinase) 계열의 구성원을 인코딩한다. 이 키나아제는 2개의 비식별 키나아제 촉매 도메인을 포함하고 있으며, MAPK(mitgen-activated kinase) 신호 경로의 멤버를 포함한 다양한 기판을 포함한다. 이 단백질의 활동은 세포 성장과 분화 를 조절하는 데 관여되어 왔다. 다른 ISO 양식 을 인코딩하는 대체 전사 스플라이스 변형이 특징지어졌다.[6]
상호작용 RPS6KA2는 MAPK3 [7] [8] MAPK1 과 상호작용 하는 것으로 나타났다.[7] [8]
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