호모사피엔스 종의 단백질 코딩 유전자
염화물 세포내 채널 단백질 2 는 인간에서 CLIC2 유전자 에 의해 암호화된 단백질 이다.[3] [4]
염화 채널은 세포막 전위의 안정화, 세포간 이동, 세포내 pH 의 유지, 세포량 조절 등 근본적인 세포 과정을 조절하는 다양한 단백질 그룹이다. 염화물 세포내 채널 2는 p64과에 속하며, 태아간과 성인의 골격근 조직에서 단백질이 검출된다. 이 유전자는 X염색체의 후보 지역에 따라 요실금 색소를 표시한다.[4]
참고 항목 참조 추가 읽기 Thiemann A, Gründer S, Pusch M, Jentsch TJ (1992). "A chloride channel widely expressed in epithelial and non-epithelial cells". Nature . 356 (6364): 57–60. Bibcode :1992Natur.356...57T . doi :10.1038/356057a0 . PMID 1311421 . S2CID 4254798 . Rogner UC, Heiss NS, Kioschis P, et al. (1997). "Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28" . Genome Res . 6 (10): 922–34. doi :10.1101/gr.6.10.922 PMID 8908511 . Singh H (2010). "Two decades with dimorphic Chloride Intracellular Channels (CLICs)" . FEBS Letters . 584 (10): 2112–21. doi :10.1016/j.febslet.2010.03.013 PMID 20226783 . Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination" . Genome Res . 10 (11): 1788–95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Rep . 1 (3): 287–92. doi :10.1093/embo-reports/kvd058 . PMC 1083732 PMID 11256614 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Dhani SU, Mohammad-Panah R, Ahmed N, et al. (2003). "Evidence for a functional interaction between the ClC-2 chloride channel and the retrograde motor dynein complex" . J. Biol. Chem . 278 (18): 16262–70. doi :10.1074/jbc.M209828200 PMID 12601004 . Fan L, Yu W, Zhu X (2003). "Interaction of Sedlin with chloride intracellular channel proteins". FEBS Lett . 540 (1–3): 77–80. doi :10.1016/S0014-5793(03)00228-X . PMID 12681486 . S2CID 8573651 . Board PG, Coggan M, Watson S, et al. (2005). "CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels". Int. J. Biochem. Cell Biol . 36 (8): 1599–612. doi :10.1016/j.biocel.2004.01.026 . PMID 15147738 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline" . Genome Res . 14 (10B): 2136–44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome" . Nature . 434 (7031): 325–37. Bibcode :2005Natur.434..325R . doi :10.1038/nature03440 . PMC 2665286 PMID 15772651 . Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics . 5 (15): 3876–84. doi :10.1002/pmic.200401239 . PMID 16130169 . S2CID 26007149 . Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415–8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 . 외부 링크 이 기사는 공공영역 에 있는 미국 국립 의학 도서관 의 텍스트를 통합하고 있다.
