호모사피엔스 종의 단백질 코딩 유전자
염화 채널 CLIC 유사 1 은 CLCC1 로도 알려진 인간의 유전자다.[5] [6]
이 유전자에 의해 인코딩된 단백질 은 염화물 채널 로, S. 세레비시아 CLCC1은 내소성 망막 과 골지 기구 를 포함한 세포내 구획의 막에 위치한다. 고환에서 고도로 표현되며 비장, 간, 신장, 심장, 뇌, 폐에서 적당히 표현된다.[6]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000121940 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000027884 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (5): 277–86. doi :10.1093/dnares/5.5.277 PMID 9872452 . ^ a b Nagasawa M, Kanzaki M, Iino Y, Morishita Y, Kojima I (June 2001). "Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus" . J. Biol. Chem . 276 (23): 20413–8. doi :10.1074/jbc.M100366200 PMID 11279057 . 추가 읽기 Nagase T, Ishikawa K, Suyama M, et al. (1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (5): 277–86. doi :10.1093/dnares/5.5.277 PMID 9872452 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 . Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions" . Genome Res . 14 (9): 1711–8. doi :10.1101/gr.2435604 . PMC 515316 PMID 15342556 . Nagasawa M, Kanzaki M, Iino Y, et al. (2001). "Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus" . J. Biol. Chem . 276 (23): 20413–8. doi :10.1074/jbc.M100366200 PMID 11279057 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 .
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