칼륨 전압 게이트 채널 서브 패밀리 V 멤버 1 은 인간에서 KCNV1 유전자 에 의해 인코딩되는 단백질 이다.[5] [6] 이 유전자에 의해 인코딩 된 단백질은 전압 정량 칼륨 채널 서브유닛이다.[5] [6]
KCNV1 유전자의 일반적인 변화는 정신분열증과 관련이 있다.[7]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000164794 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG00000022342 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattei MG, Lazdunski M (Aug 1996). "Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels" . EMBO J . 15 (13): 3322–31. doi :10.1002/j.1460-2075.1996.tb00697.x . PMC 451895 PMID 8670833 . ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev . 57 (4): 473–508. doi :10.1124/pr.57.4.10 . PMID 16382104 . S2CID 219195192 . ^ Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014-07-24). "Biological insights from 108 schizophrenia-associated genetic loci" . Nature . 511 (7510): 421–427. Bibcode :2014Natur.511..421S . doi :10.1038/nature13595 . ISSN 1476-4687 . PMC 4112379 PMID 25056061 . 추가 읽기 Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Sano A, Mikami M, Nakamura M, et al. (2002). "Positional candidate approach for the gene responsible for benign adult familial myoclonic epilepsy" . Epilepsia . 43 Suppl 9: 26–31. doi :10.1046/j.1528-1157.43.s.9.7.x PMID 12383276 . S2CID 39236204 . Ebihara M, Ohba H, Kikuchi M, Yoshikawa T (2004). "Structural characterization and promoter analysis of human potassium channel Kv8.1 (KCNV1) gene". Gene . 325 : 89–96. doi :10.1016/j.gene.2003.09.044 . PMID 14697513 . Salinas M, de Weille J, Guillemare E, et al. (1997). "Modes of regulation of shab K+ channel activity by the Kv8.1 subunit" . J. Biol. Chem . 272 (13): 8774–80. doi :10.1074/jbc.272.13.8774 PMID 9079713 .
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