호모사피엔스 종의 단백질 코딩 유전자
H+ /Cl− 교환 트랜스포터 3 은 인간 내 CLCN3 유전자 에 의해 인코딩 되는 단백질이다.[5]
상호작용 CLCN3은 PDZK1 과 상호작용 하는 것으로 나타났다.[6]
참고 항목 참조 추가 읽기 Borsani G, Rugarli EI, Taglialatela M, Wong C, Ballabio A (1995). "Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein". Genomics . 27 (1): 131–41. doi :10.1006/geno.1995.1015 . PMID 7665160 . Taine L, Coupry I, Boisseau P, Saura R, Lacombe D, Arveiler B (1998). "Refined localisation of the voltage-gated chloride channel, CLCN3, to 4q33". Hum. Genet . 102 (2): 178–81. doi :10.1007/s004390050673 . PMID 9521585 . S2CID 22138203 . Shepard AR, Rae JL (1998). "Ion transporters and receptors in cDNA libraries from lens and cornea epithelia". Curr. Eye Res . 17 (7): 708–19. doi :10.1080/02713689808951247 . PMID 9678416 . Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR (1998). "Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome" . EMBO J . 17 (23): 6879–87. doi :10.1093/emboj/17.23.6879 . PMC 1171036 PMID 9843494 . Lamb FS, Clayton GH, Liu BX, Smith RL, Barna TJ, Schutte BC (1999). "Expression of CLCN voltage-gated chloride channel genes in human blood vessels". J. Mol. Cell. Cardiol . 31 (3): 657–66. doi :10.1006/jmcc.1998.0901 . PMID 10198195 . Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination" . Genome Res . 10 (11): 1788–95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Huang P, Liu J, Di A, Robinson NC, Musch MW, Kaetzel MA, Nelson DJ (2001). "Regulation of human CLC-3 channels by multifunctional Ca2+/calmodulin-dependent protein kinase" . J. Biol. Chem . 276 (23): 20093–100. doi :10.1074/jbc.M009376200 PMID 11274166 . Lamb FS, Graeff RW, Clayton GH, Smith RL, Schutte BC, McCray PB (2001). "Ontogeny of CLCN3 chloride channel gene expression in human pulmonary epithelium". Am. J. Respir. Cell Mol. Biol . 24 (4): 376–81. doi :10.1165/ajrcmb.24.4.4114 . PMID 11306429 . Ogura T, Furukawa T, Toyozaki T, Yamada K, Zheng YJ, Katayama Y, Nakaya H, Inagaki N (2002). "ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC". FASEB J . 16 (8): 863–5. doi :10.1096/fj.01-0845fje . PMID 11967229 . S2CID 33470444 . Hermoso M, Satterwhite CM, Andrade YN, Hidalgo J, Wilson SM, Horowitz B, Hume JR (2002). "ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes" . J. Biol. Chem . 277 (42): 40066–74. doi :10.1074/jbc.M205132200 PMID 12183454 . Gentzsch M, Cui L, Mengos A, Chang XB, Chen JH, Riordan JR (2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins" . J. Biol. Chem . 278 (8): 6440–9. doi :10.1074/jbc.M211050200 PMID 12471024 . Jin NG, Kim JK, Yang DK, Cho SJ, Kim JM, Koh EJ, Jung HC, So I, Kim KW (2003). "Fundamental role of ClC-3 in volume-sensitive Cl- channel function and cell volume regulation in AGS cells". Am. J. Physiol. Gastrointest. Liver Physiol . 285 (5): G938-48. doi :10.1152/ajpgi.00470.2002 . PMID 12842831 . Olsen ML, Schade S, Lyons SA, Amaral MD, Sontheimer H (2003). "Expression of voltage-gated chloride channels in human glioma cells" . J. Neurosci . 23 (13): 5572–82. doi :10.1523/JNEUROSCI.23-13-05572.2003 PMC 6741216 PMID 12843258 . Salazar G, Love R, Styers ML, Werner E, Peden A, Rodriguez S, Gearing M, Wainer BH, Faundez V (2004). "AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells" . J. Biol. Chem . 279 (24): 25430–9. doi :10.1074/jbc.M402331200 PMID 15073168 . Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline" . Genome Res . 14 (10B): 2136–44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Zhou JG, Ren JL, Qiu QY, He H, Guan YY (2005). "Regulation of intracellular Cl- concentration through volume-regulated ClC-3 chloride channels in A10 vascular smooth muscle cells" . J. Biol. Chem . 280 (8): 7301–8. doi :10.1074/jbc.M412813200 PMID 15596438 . Yeung CH, Barfield JP, Cooper TG (2005). "Chloride channels in physiological volume regulation of human spermatozoa" . Biol. Reprod . 73 (5): 1057–63. doi :10.1095/biolreprod.105.044123 PMID 16033995 . Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415-8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 .
외부 링크 이 기사는 공공영역 에 있는 미국 국립 의학 도서관 의 텍스트를 통합하고 있다.
