IFN-알파-1 /13이라고 도 알려진 인터페론 알파-1/13 은 인간에서 IFNA1 과 IFNA13 유전자 에 의해 암호화된 단백질 이다.[3] [4]
참조 추가 읽기 Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes" . Biochem. J . 329 (2): 295–302. doi :10.1042/bj3290295 . PMC 1219044 PMID 9425112 . Davila S, Froeling FE, Tan A, et al. (2010). "New genetic associations detected in a host response study to hepatitis B vaccine" . Genes Immun . 11 (3): 232–8. doi :10.1038/gene.2010.1 PMID 20237496 . Weber H, Weissmann C (1983). "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli" . Nucleic Acids Res . 11 (16): 5661–9. doi :10.1093/nar/11.16.5661 . PMC 326304 PMID 6310510 . Lamesch P, Li N, Milstein S, et al. (2007). "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes" . Genomics . 89 (3): 307–15. doi :10.1016/j.ygeno.2006.11.012 . PMC 4647941 PMID 17207965 . Goeddel DV, Leung DW, Dull TJ, et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature . 290 (5801): 20–6. Bibcode :1981Natur.290...20G . doi :10.1038/290020a0 . PMID 6163083 . S2CID 1900300 . Myers MP, Andersen JN, Cheng A, et al. (2001). "TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B" . J. Biol. Chem . 276 (51): 47771–4. doi :10.1074/jbc.C100583200 PMID 11694501 . Hussain M, Ni D, Gill D, Liao MJ (2000). "IFN-alpha1a gene is the major variant in the North American population". J. Interferon Cytokine Res . 20 (9): 763–8. doi :10.1089/10799900050151021 . PMID 11032395 . Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 PMID 15164053 . Siezen CL, Bont L, Hodemaekers HM, et al. (2009). "Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes". Pediatr. Infect. Dis. J . 28 (4): 333–5. doi :10.1097/INF.0b013e31818e2aa9 . PMID 19258923 . S2CID 25601837 . Hardy MP, Owczarek CM, Jermiin LS, et al. (2004). "Characterization of the type I interferon locus and identification of novel genes". Genomics . 84 (2): 331–45. doi :10.1016/j.ygeno.2004.03.003 . PMID 15233997 . Silva LK, Blanton RE, Parrado AR, et al. (2010). "Dengue hemorrhagic fever is associated with polymorphisms in JAK1" . Eur. J. Hum. Genet . 18 (11): 1221–7. doi :10.1038/ejhg.2010.98 . PMC 2950898 PMID 20588308 . Janssen R, Bont L, Siezen CL, et al. (2007). "Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes". J. Infect. Dis . 196 (6): 826–34. doi :10.1086/520886 . PMID 17703412 . Shuai K, Horvath CM, Huang LH, et al. (1994). "Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions". Cell . 76 (5): 821–8. doi :10.1016/0092-8674(94)90357-3 . PMID 7510216 . S2CID 41612814 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its biochemistry" . J. Biol. Chem . 267 (8): 5017–20. doi :10.1016/S0021-9258(18)42719-6 PMID 1371992 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest" . Mol. Cell. Biol . 16 (7): 3934–44. doi :10.1128/MCB.16.7.3934 . PMC 231390 PMID 8668211 . Nagata S, Mantei N, Weissmann C (1980). "The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha". Nature . 287 (5781): 401–8. Bibcode :1980Natur.287..401N . doi :10.1038/287401a0 . PMID 6159536 . S2CID 29500779 . Todokoro K, Kioussis D, Weissmann C (1984). "Two non-allelic human interferon alpha genes with identical coding regions" . EMBO J . 3 (8): 1809–12. doi :10.1002/j.1460-2075.1984.tb02050.x . PMC 557600 PMID 6479148 . Schuurhof A, Bont L, Siezen CL, et al. (2010). "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls". Pediatr. Pulmonol . 45 (6): 608–13. doi :10.1002/ppul.21229 . PMID 20503287 . S2CID 24678182 . IFNA13 은 인터페론 유전자다.
케모킨 CSF
인터페론
IFNAR(α/β, I) 고민자: 알빈터페론 인터페론 알파(인터페론 알파, IFN-α) Interferon alfa (IFNA1 , IFNA2 , IFNA4 , IFNA5 , IFNA6 , IFNA7 , IFNA8 , IFNA10 , IFNA13 , IFNA14 , IFNA16 , IFNA17 , IFNA21 )인터페론 알파 2a 인터페론 알파 2b 인터페론 알파 n1 인터페론 알파콘-1 인터페론 알파-n3 인터페론 베타(IFN-β)( IFNB1 , IFNB3 )인터페론 베타 1a 인터페론 베타 1b 인터페론 카파(IFN-filename/changes/changes/changes, IFNK) 인터페론 오메가(IFN-Ω, IFNW1) 페긴터페론 알파-2a 페긴터페론 알파-2b IFNGR (1998, II) IFNLR (1998, III) 대신 여기 서 IL-28R(IFNLR)을 참조하십시오.
인터루킨 TGFβ TNF 다른이들
