펜타레인 A

Pentarane A
펜타레인 A
Pentarane A.svg
임상자료
기타 이름D'6-펜타레인, 프레그나-D'6-펜타레인, 16α-17α-사이클로헥사노프로게스테론, 16α-17α-테트라메틸엔페 빈센트-4-ene-3,20-dione, 17α-아세틸-아세틸-16β, 24-사이클로-21-노르철-4-엔-3-one
식별자
  • (4aR,4bS,6aS,6bS,10aR,11aS,11bR)-6b-Acetyl-4a,6a-dimethyl-4,4b,5,6,7,8,9,10,10a,11,11a,11b,12,13-tetradecahydro-3H-indeno[2,1-a]phenanthren-2-one
CAS 번호
펍켐 CID
켐스파이더
CompTox 대시보드 (EPA)
화학 및 물리적 데이터
공식C25H36O2
어금질량368.561 g·1998−1
3D 모델(JSmol)
  • CC(=O)[C@]12CCC[C@H]1C[C@@H]1C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CCC5=CC(=O)CC[C@]45C)c
  • InChI=1S/C25H36O2/c1-16(26)25-11-5-4-6-18(25)15-22-20-8-7-17-14-19(27)9-12-23(17,2)21(20)10-13-24(22,25)3/h14,18,20-22H,4-13,15H2,1-3H3/t18-,20-,21+,22+,23+,24+,25+/m1/s1
  • 키:QRVBGQLTPQQFJY-IEHCJHDVSA-N

Pentarane A, also known as D'6-pentarane or pregna-D'6-pentarane, as well as 16α,17α-cyclohexanoprogesterone, 16α,17α-tetramethylenepregn-4-ene-3,20-dione, or 17α-acetyl-16β,24-cyclo-21-norchol-4-en-3-one, is a steroidal progestin that was developed by the Zelinskii Institute of Organic Chemistry of the Russian Academy of Sciences and was never markited.[1][2] 펜타레인 A의 6α-메틸화 아날로그메시스톤 또는 펜타레인 B로 알려져 있다.[2]

참고 항목

참조

  1. ^ Kamernitzky AV, Levina IS, Kulikova LE, Ignatov VN, Korkhov VV, Nikitina GV, Terekhina AI (1982). "Pregna-D'-pentaranes - a new class of active gestagenes". J. Steroid Biochem. 16 (1): 61–7. doi:10.1016/0022-4731(82)90144-3. PMID 7062740.
  2. ^ a b Bhakta, Amrita; Herman, Michelle; Levina, Inna S.; Moudgil, V. K. (1993). "Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol". Molecular and Cellular Biochemistry. 125 (2): 153–161. doi:10.1007/BF00936444. ISSN 0300-8177. PMID 8283970. S2CID 20319611.