호모 사피엔스 종의 단백질 코드 유전자
진핵생물번역개시인자 5B는 EIF5B 유전자에 [5] [6] [7] 단백질 이다.
진핵생물 에서 번역의 정확한 시작은 복잡하고 많은 요소들을 필요로 하며, 그 중 일부는 여러 개의 소단위들로 구성되어 있다.시작 인자가 3개 (IF1, IF2, IF3)인 박테리아 에서 이 과정이 더 간단하다.이러한 요인 중 두 가지는 진핵생물에서 보존된다: IF1의 상동성은 eIF1A이고 IF2의 상동성은 eIF5B이다. 이 유전자는 eIF5B를 암호화한다. eIF1A 및 eIF5B 인자는 다른 개시인자 및 GTP와 함께 리보솜 상에서 상호작용하여 mRNA의 개시코돈 에 개시메티오닌 tRNA를 위치시켜 정확하게 변환을 [7]
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