EIF3H

EIF3H
사용 가능한 구조
PDB	Ortholog 검색: PDBe RCSB
PDB ID 코드 목록
	3J8B, 3J8C
식별자
에일리어스	EIF3H, EIF3S3, eIF3-gamma, eIF3-p40, 진핵생물 번역 개시인자 3 서브유닛 H
외부 ID	OMIM: 603912 MGI: 1915385 HomoloGene: 2785 GeneCard: EIF3H
유전자 위치(인간)
크르.	8번 염색체(인간)
끝.	116,766,925 bp
유전자 위치(마우스)
크르.	15번 염색체(쥐)
끝.	51,728,919 bp
RNA발현패턴
	상단 표시 위치:
	신경절 융기; ; 이하선; ; 단구; ; 자궁경관; ; 림프절; ; 췌장체; ; 두정 흉막; ; 위점막; ; 경골; ; 직장;
	상단 표시 위치:
	노른자낭; ; 입술; ; 모룰라; ; 발목 관절; ; 상전두회; ; 정자질; ; 정자 세포; ; 흉선; ; 식도; ; 소뇌 피질;
	추가 참조 표현식 데이터
	; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	단백질 결합; 번역 개시 인자 활성; RNA결합; 메탈로펩티드가수분해효소활성;
셀룰러 컴포넌트	세포질; 세포; 진핵생물번역개시인자3복합체; 진핵생물 번역 개시인자 3 복합체, eIF3m; 세포외 엑소좀; 막; 진핵생물43S사전개시복합체; 진핵생물48S사전개시복합체; 다염색체리보솜;
생물학적 과정	번역 개시; 번역 개시 조절; 단백질생합성; 세포질 번역 개시 복합체 형성; 세포질 번역 개시; 단백질 분해;
	출처:아미고 / QuickGO
맞춤법
	8667
	68135
	ENSG00000147677
	ENSMUSG000022312
	O15372
	Q91WK2
	NM_003756
	NM_080635
	NP_003747
	NP_542366
	위키데이터
인간 보기/편집	마우스 표시/편집

진핵생물 번역 개시 인자 3 서브유닛 H(eIF3h)는 EIF3H ^[5]^[6]유전자에 의해 인체 내에서 암호화되는 단백질이다.

상호 작용

eIF3h는 eIF3a와 ^[7]^[8]^[9]상호작용하는 것으로 나타났습니다.

「」를 참조해 주세요.

진핵생물개시인자3(eIF3)

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG0000014767 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000022312 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
^ "Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa".
^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
^ Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

추가 정보

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3". J. Biol. Chem. 272 (2): 1101–9. doi:10.1074/jbc.272.2.1101. PMID 8995409.
Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc.272.2.1110. PMID 8995410.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.
Saramäki O, Willi N, Bratt O, Gasser TC, Koivisto P, Nupponen NN, Bubendorf L, Visakorpi T (2001). "Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer". Am. J. Pathol. 159 (6): 2089–94. doi:10.1016/S0002-9440(10)63060-X. PMC 1850612. PMID 11733359.
Morris JA, Kandpal G, Ma L, Austin CP (2003). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation". Hum. Mol. Genet. 12 (13): 1591–608. doi:10.1093/hmg/ddg162. PMID 12812986.
Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J (2003). "PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas". Hepatology. 38 (5): 1242–9. doi:10.1053/jhep.2003.50457. PMID 14578863. S2CID 21888517.
Savinainen KJ, Linja MJ, Saramäki OR, Tammela TL, Chang GT, Brinkmann AO, Visakorpi T (2004). "Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer". Br. J. Cancer. 90 (5): 1041–6. doi:10.1038/sj.bjc.6601648. PMC 2409619. PMID 14997205.
Savinainen KJ, Helenius MA, Lehtonen HJ, Visakorpi T (2006). "Overexpression of EIF3S3 promotes cancer cell growth". Prostate. 66 (11): 1144–50. doi:10.1002/pros.20452. PMID 16652384. S2CID 2281409.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

외부 링크

PDB for UniProt: O15372(유핵 번역 개시 인자 3 서브유닛 H)에서 PDB에서 사용 가능한 모든 구조 정보의 개요.

인간 염색체 8번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG0000014767 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000022312 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9341143-5] Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.

[entrez-6] "Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa".

[pmid17353931-7] Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

[pmid14519125-8] Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.

[pmid9822659-9] Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

Search

EIF3H

네임스페이스

더

목차

상호 작용

「」를 참조해 주세요.

레퍼런스

추가 정보

외부 링크

Search

EIF3H

상호 작용

「 」를 참조해 주세요.

레퍼런스

추가 정보

외부 링크

「」를 참조해 주세요.