호모 사피엔스 종의 단백질 코드 유전자
EIF3K 식별자 에일리어스 EIF3K 외부 ID OMIM : 609596 MGI : 1921080 HomoloGene : 8292 GenCard : EIF3K 위키데이터
진핵생물 번역 개시 인자 3 서브유닛 K(eIF3k )는 EIF3K [5] [6] [7] 단백질 이다.
기능. ~800kDa 진핵생물 개시인자 3(eIF3)은 가장 큰 eIF 이며 eIF3k/EIF2S12를 포함하여 최소 12개의 서브유닛을 포함하고 있다. eIF3는 40S 리보솜 서브유닛에 직접 결합하고 43S 프리개시 [8] [7]
상호 작용 eIF3k는 Cyclin D3 [9] [6] [10] eIF3a 와 상호작용하는 것 으로 나타났습니다.
「 」를 참조해 주세요. 레퍼런스 ^ a b c ENSG00000282986 GRCh38: 앙상블 릴리즈 89: ENSG00000178982, ENSG00000282986 : Ensembl , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000053565 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, et al. (October 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells" . Genome Research . 10 (10): 1546–60. doi :10.1101/gr.140200 . PMC 310934 PMID 11042152 . ^ a b Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3" . European Journal of Biochemistry . 270 (20): 4133–9. doi :10.1046/j.1432-1033.2003.03807.x PMID 14519125 . ^ a b "Entrez Gene: EIF3S12 eukaryotic translation initiation factor 3, subunit 12" .^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3" . European Journal of Biochemistry . 270 (20): 4133–9. doi :10.1046/j.1432-1033.2003.03807.x PMID 14519125 . ^ Shen X, Yang Y, Liu W, Sun M, Jiang J, Zong H, Gu J (August 2004). "Identification of the p28 subunit of eukaryotic initiation factor 3 (eIF3k) as a new interaction partner of cyclin D3" . FEBS Letters . 573 (1–3): 139–46. doi :10.1016/j.febslet.2004.07.071 PMID 15327989 . S2CID 16005938 . ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Molecular Systems Biology . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
추가 정보 Karki S, Ligon LA, DeSantis J, Tokito M, Holzbaur EL (May 2002). "PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact" . Molecular Biology of the Cell . 13 (5): 1722–34. doi :10.1091/mbc.02-02-0011 . PMC 111139 PMID 12006665 . Wei Z, Zhang P, Zhou Z, Cheng Z, Wan M, Gong W (August 2004). "Crystal structure of human eIF3k, the first structure of eIF3 subunits" . The Journal of Biological Chemistry . 279 (33): 34983–90. doi :10.1074/jbc.M405158200 PMID 15180986 . Shen X, Yang Y, Liu W, Sun M, Jiang J, Zong H, Gu J (August 2004). "Identification of the p28 subunit of eukaryotic initiation factor 3(eIF3k) as a new interaction partner of cyclin D3" . FEBS Letters . 573 (1–3): 139–46. doi :10.1016/j.febslet.2004.07.071 PMID 15327989 . S2CID 16005938 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . 외부 링크 PDB for UniProt: Q9 PDBe-KB 에서의 UBQ5(인간 진핵생물 번역 개시 인자 3 서브유닛 K(EIF3K)).
