호모 사피엔스 종의 단백질 코드 유전자
유비퀴틴 결합효소 E2B 는 인체에서 UBE2B [5] [6] 유전자에 의해 암호화되는 단백질 이다.
유비퀴틴에 의한 단백질의 변형은 분해를 위해 비정상적이거나 단명한 단백질을 목표로 하는 중요한 세포 메커니즘이다. 유비퀴티네이션은 유비퀴틴 활성화 효소 또는 E1s, 유비퀴틴 결합 효소 또는 E2s 및 유비퀴틴 단백질 결합효소, E3s의 최소 세 가지 종류의 효소를 포함한다. 이 유전자는 E2 유비퀴틴 결합 효소군의 일원을 암호화한다. 이 효소는 복제 후 DNA 손상 복구에 필요합니다. 그것의 단백질 배열은 생쥐, 쥐, 토끼 상동체와 100% 동일하며, 이는 진핵생물 [6] 진화에 있어서 이 효소가 보존성이 높다는 것을 나타낸다.
상호 작용 UBE2B는 RAD18 과 [7] [8] 상호작용하는 것 으로 나타났습니다.
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