ADP/ATP 트랜스로케이스 3

SLC25A6
식별자
에일리어스	SLC25A6, ADP/ATP 전이효소 3, 용질담체 패밀리 25 멤버 6, AAC3, ANT2, ANT3, ANT3Y, ANT
외부 ID	OMIM: 300151, 403000 HomoloGene: 68194 GenCard: SLC25A6
유전자 위치(인간)
크르.	X염색체(인간)
끝.	1,392,139 bp
RNA발현패턴
	상단 표시 위치:
	신장수질; ; 니플; ; 태아; ; 유문; ; 외음부; ; 위체; ; 신경절 융기; ; 갑상선 우엽; ; 좌부신; ; 뇌하수체 전엽;
	없음
	추가 참조 표현식 데이터
	없음
유전자 존재론
분자 함수	수송체 활성; 단백질 결합; 아데닌경막수송활성; ATP: ADP 안티포터 액티비티; 막전송체활성;
셀룰러 컴포넌트	막; TIM23 미토콘드리아 수입내막전달효소복합체; 미토콘드리아; 미토콘드리아 내막; 핵; 세포외 매트릭스; 막의 적분 성분;
생물학적 과정	인슐린 분비 조절; 미토콘드리아를 표적으로 하는 단백질; 막 통과 수송; 아포토시스 과정; ADP 트랜스포트; ATP 수송; 바이러스 과정; 아데닌수송; 미토콘드리아막투과성조절; 운송;
	출처:아미고 / QuickGO
맞춤법
	293
	없음
	ENSG00000169100
	없음
	P12236; Q6I9V5
	없음
	NM_001636
	없음
	NP_001627; NP_001627.2
	없음
	위키데이터
인간 보기/편집

ADP/ATP 트랜스로카아제 3은 용질담체 패밀리 25 멤버 6이라고도 하며, SLC25A6 ^[3]유전자에 의해 인체 내에서 암호화되는 단백질이다.

이 유전자의 동일한 복사본이 X ^[4]및 Y 염색체의 의사 자가 염색체 영역에 존재한다.

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레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000169100 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Palmieri F (February 2004). "The mitochondrial transporter family (SLC25): physiological and pathological implications". Pflügers Arch. 447 (5): 689–709. doi:10.1007/s00424-003-1099-7. PMID 14598172. S2CID 25304722.
^ Slim R, Levilliers J, Lüdecke HJ, Claussen U, Nguyen VC, Gough NM, Horsthemke B, Petit C (April 1993). "A human pseudoautosomal gene encodes the ANT3 ADP/ATP translocase and escapes X-inactivation". Genomics. 16 (1): 26–33. doi:10.1006/geno.1993.1135. PMID 8486369.

추가 정보

Jang JY, Lee CE (2003). "Mitochondrial adenine nucleotide translocator 3 is regulated by IL-4 and IFN-gamma via STAT-dependent pathways". Cell. Immunol. 226 (1): 11–9. doi:10.1016/j.cellimm.2003.11.004. PMID 14746803.
Komaki H, Fukazawa T, Houzen H, et al. (2002). "A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external ophthalmoplegia patients with mitochondrial DNA with multiple deletions". Ann. Neurol. 51 (5): 645–8. doi:10.1002/ana.10172. PMID 12112115. S2CID 38767585.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Majima E, Takeda M, Miki S, et al. (2002). "Close location of the first loop to the third loop of the mitochondrial ADP/ATP carrier deduced from cross-linking catalyzed by copper-o-phenanthroline of the solubilized carrier with Triton X-100". J. Biochem. 131 (3): 461–8. doi:10.1093/oxfordjournals.jbchem.a003122. PMID 11872176.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Zamora M, Granell M, Mampel T, Viñas O (2004). "Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells". FEBS Lett. 563 (1–3): 155–60. doi:10.1016/S0014-5793(04)00293-5. PMID 15063741. S2CID 36314858.
Hu Z, Guo X, Yu Q, et al. (2009). "Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells". FEBS Lett. 583 (2): 383–8. doi:10.1016/j.febslet.2008.12.029. PMID 19111545.
De Marcos Lousa C, Trézéguet V, Dianoux AC, et al. (2002). "The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae". Biochemistry. 41 (48): 14412–20. doi:10.1021/bi0261490. PMID 12450408.
Zamora M, Ortega JA, Alaña L, et al. (2006). "Apoptotic and anti-proliferative effects of all-trans retinoic acid. Adenine nucleotide translocase sensitizes HeLa cells to all-trans retinoic acid". Exp. Cell Res. 312 (10): 1813–9. doi:10.1016/j.yexcr.2006.02.014. PMID 16556444.
Yang Z, Cheng W, Hong L, et al. (2007). "Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells". Mol. Biol. Cell. 18 (11): 4681–9. doi:10.1091/mbc.E06-12-1161. PMC 2043556. PMID 17855512.
Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells". Mol. Cell. Proteomics. 6 (4): 575–88. doi:10.1074/mcp.M600249-MCP200. PMID 17220478.
Mühlenbein N, Hofmann S, Rothbauer U, Bauer MF (2004). "Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria". J. Biol. Chem. 279 (14): 13540–6. doi:10.1074/jbc.M312485200. PMID 14726512.
Verrier F, Mignotte B, Jan G, Brenner C (2003). "Study of PTPC composition during apoptosis for identification of viral protein target" (PDF). Ann. N. Y. Acad. Sci. 1010 (1): 126–42. Bibcode:2003NYASA1010..126V. doi:10.1196/annals.1299.022. PMID 15033708. S2CID 22660199.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Napoli L, Bordoni A, Zeviani M, et al. (2001). "A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family". Neurology. 57 (12): 2295–8. doi:10.1212/wnl.57.12.2295. PMID 11756613. S2CID 10284753.
Chanturiya AN, Basañez G, Schubert U, et al. (2004). "PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes". J. Virol. 78 (12): 6304–12. doi:10.1128/JVI.78.12.6304-6312.2004. PMC 416516. PMID 15163724.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Jang JY, Lee CE (2006). "IL-4-induced upregulation of adenine nucleotide translocase 3 and its role in Th cell survival from apoptosis". Cell. Immunol. 241 (1): 14–25. doi:10.1016/j.cellimm.2006.07.006. PMID 16930576.
Zamarin D, García-Sastre A, Xiao X, et al. (2005). "Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1". PLOS Pathog. 1 (1): e4. doi:10.1371/journal.ppat.0010004. PMC 1238739. PMID 16201016.
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인간 X 염색체 및/또는 그와 관련된 단백질의 유전자에 대한 이 기사는 스텁이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000169100 - 앙상블, 2017년 5월

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14598172-3] Palmieri F (February 2004). "The mitochondrial transporter family (SLC25): physiological and pathological implications". Pflügers Arch. 447 (5): 689–709. doi:10.1007/s00424-003-1099-7. PMID 14598172. S2CID 25304722.

[pmid8486369-4] Slim R, Levilliers J, Lüdecke HJ, Claussen U, Nguyen VC, Gough NM, Horsthemke B, Petit C (April 1993). "A human pseudoautosomal gene encodes the ANT3 ADP/ATP translocase and escapes X-inactivation". Genomics. 16 (1): 26–33. doi:10.1006/geno.1993.1135. PMID 8486369.

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