UDP갈락토오스트랜스로케이터

SLC35A2
식별자
에일리어스	SLC35A2, CDG2M, CDGX, UDP-Gal-Tr, UGALT, UGAT, UGT1, UGT2, UGTL, 용질 캐리어 패밀리 35 A2
외부 ID	OMIM : 314375 HomoloGene : 136614 GenCard : SLC35A2
유전자 위치(인간)
크르.	X염색체(인간)
끝.	48,136,958 bp
RNA발현패턴
	상단 표시 위치:
	이차 난모세포; ; 기관지 상피 세포; ; 안검결막; ; 자궁내막간질세포; ; 직장; ; 우측 자궁관; ; 경골; ; 랑게르한스 섬; ; 췌장체; ; 좌부신;
	없음
	추가 참조 표현식 데이터
	; ; ; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	단백질 결합; UDP-갈락토오스전달체활성; 피리미딘뉴클레오티드결합트랜스멤브란수송체활성;
셀룰러 컴포넌트	막의 적분 성분; 골지막; 골지 장치; 소포체; 핵; 막; 골지막의 적분 성분;
생물학적 과정	갈락토오스 대사 과정; 탄수화물 수송; UDP-갈락토오스경막수송; 피리미딘뉴클레오티드결합경막수송;
	출처:아미고 / QuickGO
맞춤법
	7355
	없음
	ENSG00000102100
	없음
	P78381
	없음
NM_005660; NM_001032289; NM_001042498; NM_001282647; NM_001282648;
	NM_001282649; NM_001282650; NM_001282651
	없음
NP_001027460; NP_001035963; NP_001269576; NP_001269577; NP_001269578;
	NP_001269579; NP_001269580; NP_005651
	없음
	위키데이터
인간 보기/편집

UDP-갈락토오스 트랜스로케이터는 SLC35A2 ^[3]^[4]유전자에 의해 인체에서 암호화되는 단백질이다.

SLC35A2 유전자의 변종은 전두엽 ^[5]간질의 하위 유형인 뇌전증(MOGHE)에서 올리고드 엔드로글리아 과형성과 함께 피질 발달의 가벼운 기형과 관련이 있다. 뇌전증

「」를 참조해 주세요.

용질 캐리어 패밀리

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000102100 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hara T, Yamauchi M, Takahashi E, Hoshino M, Aoki K, Ayusawa D, Kawakita M (November 1993). "The UDP-galactose translocator gene is mapped to band Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus". Somatic Cell and Molecular Genetics. 19 (6): 571–5. doi:10.1007/BF01233383. PMID 8128316. S2CID 10466290.
^ "Entrez Gene: SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2".
^ Bonduelle T, Hartlieb T, Baldassari S, Sim NS, Kim SH, Kang HC, et al. (January 2021). "Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)". Acta Neuropathologica Communications. 9 (1): 3. doi:10.1186/s40478-020-01085-3. PMC 7788938. PMID 33407896.

추가 정보

Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Miura N, Ishida N, Hoshino M, Yamauchi M, Hara T, Ayusawa D, Kawakita M (August 1996). "Human UDP-galactose translocator: molecular cloning of a complementary DNA that complements the genetic defect of a mutant cell line deficient in UDP-galactose translocator". Journal of Biochemistry. 120 (2): 236–41. doi:10.1093/oxfordjournals.jbchem.a021404. PMID 8889805.
Ishida N, Miura N, Yoshioka S, Kawakita M (December 1996). "Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family". Journal of Biochemistry. 120 (6): 1074–8. doi:10.1093/oxfordjournals.jbchem.a021523. PMID 9010752.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Yoshioka S, Sun-Wada GH, Ishida N, Kawakita M (October 1997). "Expression of the human UDP-galactose transporter in the Golgi membranes of murine Had-1 cells that lack the endogenous transporter". Journal of Biochemistry. 122 (4): 691–5. doi:10.1093/oxfordjournals.jbchem.a021810. PMID 9399569.
Aoki K, Ishida N, Kawakita M (June 2001). "Substrate recognition by UDP-galactose and CMP-sialic acid transporters. Different sets of transmembrane helices are utilized for the specific recognition of UDP-galactose and CMP-sialic acid". The Journal of Biological Chemistry. 276 (24): 21555–61. doi:10.1074/jbc.M101462200. PMID 11279205.
Kumamoto K, Goto Y, Sekikawa K, Takenoshita S, Ishida N, Kawakita M, Kannagi R (June 2001). "Increased expression of UDP-galactose transporter messenger RNA in human colon cancer tissues and its implication in synthesis of Thomsen-Friedenreich antigen and sialyl Lewis A/X determinants". Cancer Research. 61 (11): 4620–7. PMID 11389099.
Sprong H, Degroote S, Nilsson T, Kawakita M, Ishida N, van der Sluijs P, van Meer G (August 2003). "Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum". Molecular Biology of the Cell. 14 (8): 3482–93. doi:10.1091/mbc.E03-03-0130. PMC 181583. PMID 12925779.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

이 막단백질 관련 물품은 그루브입니다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000102100 - 앙상블, 2017년 5월

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8128316-3] Hara T, Yamauchi M, Takahashi E, Hoshino M, Aoki K, Ayusawa D, Kawakita M (November 1993). "The UDP-galactose translocator gene is mapped to band Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus". Somatic Cell and Molecular Genetics. 19 (6): 571–5. doi:10.1007/BF01233383. PMID 8128316. S2CID 10466290.

[entrez-4] "Entrez Gene: SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2".

[5] Bonduelle T, Hartlieb T, Baldassari S, Sim NS, Kim SH, Kang HC, et al. (January 2021). "Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)". Acta Neuropathologica Communications. 9 (1): 3. doi:10.1186/s40478-020-01085-3. PMC 7788938. PMID 33407896.

[1]

[2]

[3]

[4]

[5]

Search

UDP갈락토오스트랜스로케이터

네임스페이스

더

「」를 참조해 주세요.

레퍼런스

추가 정보

Search

UDP갈락토오스트랜스로케이터

「 」를 참조해 주세요.

레퍼런스

추가 정보

「」를 참조해 주세요.