CMP-시알산수송체

SLC35A1
식별자
에일리어스	SLC35A1, CDG2F, CMPST, CST, hCST, 용질 캐리어 패밀리 35(CMP-시알산 트랜스포터), 부재 A1, 용질 캐리어 패밀리 35 멤버 A1
외부 ID	OMIM : 605634 MGI : 1345622 HomoloGene : 38181 GenCard : SLC35A1
유전자 위치(인간)
크르.	6번 염색체(인간)
끝.	87,136,336 bp
유전자 위치(마우스)
크르.	4번 염색체(쥐)
끝.	34,687,438 bp
RNA발현패턴
	상단 표시 위치:
	단구; ; 직장; ; 오른쪽 폐; ; 아킬레스건; ; 소뇌 반구; ; 횡결장; ; 자궁내막; ; 평활근 조직; ; 브로드만 9구역; ; 좌부신;
	상단 표시 위치:
	결막공; ; 좌결장; ; 각막; ; 턱밑샘; ; 각막 간질; ; 파네스 세포; ; 위상피; ; 망막 색소 상피; ; 좌골 신경; ; 섬모체;
	추가 참조 표현식 데이터
	없음
유전자 존재론
분자 함수	CMP-N-아세틸뉴라민트랜스막수송체활성; 피리미딘뉴클레오티드결합트랜스멤브란수송체활성; 시알산전달체활성;
셀룰러 컴포넌트	막의 적분 성분; 골지막; 골지 장치; 혈장막의 적분 성분; 막; 골지막의 적분 성분;
생물학적 과정	CMP-N-아세틸뉴라민트막간수송; 탄수화물 수송; 탄수화물 대사 과정; 피리미딘뉴클레오티드결합경막수송; 시알산 수송;
	출처:아미고 / QuickGO
맞춤법
	10559
	24060
	ENSG00000164414
	ENSMUSG000028293
	P78382
	Q61420
	NM_006416; NM_001168398
	NM_011895
	NP_001161870; NP_006407
	NP_036025
	위키데이터
인간 보기/편집	마우스 표시/편집

CMP-시알산 트랜스포터는 SLC35A1 ^[5]^[6]^[7]유전자에 의해 인체 내에서 암호화되는 단백질이다.

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용질 캐리어 패밀리

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000164414 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000028293 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishida N, Miura N, Yoshioka S, Kawakita M (Apr 1997). "Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family". J Biochem. 120 (6): 1074–8. doi:10.1093/oxfordjournals.jbchem.a021523. PMID 9010752.
^ Ishida N, Ito M, Yoshioka S, Sun-Wada GH, Kawakita M (Sep 1998). "Functional expression of human golgi CMP-sialic acid transporter in the Golgi complex of a transporter-deficient Chinese hamster ovary cell mutant". J Biochem. 124 (1): 171–8. doi:10.1093/oxfordjournals.jbchem.a022076. PMID 9644260.
^ "Entrez Gene: SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1".

추가 정보

Wahlberg JE (1976). "Sensitization and testing of guinea pigs with nickel sulfate". Dermatologica. 152 (6): 321–30. doi:10.1159/000251278. PMID 964426.
Harvey BE, Thomas P (1993). "Inhibition of CMP-sialic acid transport in human liver and colorectal cancer cell lines by a sialic acid nucleoside conjugate (KI-8110)". Biochem. Biophys. Res. Commun. 190 (2): 571–5. doi:10.1006/bbrc.1993.1086. PMID 8427599.
Lennon G, Auffray C, Polymeropoulos M, Soares MB (1996). "The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression". Genomics. 33 (1): 151–2. doi:10.1006/geno.1996.0177. PMID 8617505.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Aoki K, Ishida N, Kawakita M (2003). "Substrate recognition by nucleotide sugar transporters: further characterization of substrate recognition regions by analyses of UDP-galactose/CMP-sialic acid transporter chimeras and biochemical analysis of the substrate specificity of parental and chimeric transporters". J. Biol. Chem. 278 (25): 22887–93. doi:10.1074/jbc.M302620200. PMID 12682060.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Martinez-Duncker I, Dupré T, Piller V, et al. (2005). "Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter". Blood. 105 (7): 2671–6. doi:10.1182/blood-2004-09-3509. PMID 15576474. S2CID 13582151.
Misaki R, Fujiyama K, Seki T (2006). "Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell". Biochem. Biophys. Res. Commun. 339 (4): 1184–9. doi:10.1016/j.bbrc.2005.11.130. PMID 16343442.
Zhao W, Chen TL, Vertel BM, Colley KJ (2006). "The CMP-sialic acid transporter is localized in the medial-trans Golgi and possesses two specific endoplasmic reticulum export motifs in its carboxyl-terminal cytoplasmic tail". J. Biol. Chem. 281 (41): 31106–18. doi:10.1074/jbc.M605564200. PMID 16923816.

외부 링크

글리코실화 선천성 장애에 대한 Gen Reviews/NCBI/NIH/UW 엔트리 개요

이 막단백질 관련 물품은 그루브입니다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000164414 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000028293 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9010752-5] Ishida N, Miura N, Yoshioka S, Kawakita M (Apr 1997). "Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family". J Biochem. 120 (6): 1074–8. doi:10.1093/oxfordjournals.jbchem.a021523. PMID 9010752.

[pmid9644260-6] Ishida N, Ito M, Yoshioka S, Sun-Wada GH, Kawakita M (Sep 1998). "Functional expression of human golgi CMP-sialic acid transporter in the Golgi complex of a transporter-deficient Chinese hamster ovary cell mutant". J Biochem. 124 (1): 171–8. doi:10.1093/oxfordjournals.jbchem.a022076. PMID 9644260.

[entrez-7] "Entrez Gene: SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1".

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