방향족 아미노산 트랜스포터 1 과 T형 아미노산 트랜스포터 1 (TAT1) 및 솔루트 운반체 16 멤버 10 (SLC16A10)으로도 알려진 모노카르복실산트 트랜스포터 10(MCT 10)은 인체에서 SLC16A10 유전자 에 의해 인코딩 되는 단백질이다.[5] [6] [7] SLC16A10은 솔루트 캐리어 계열 의 일원이다.
함수 SLC16A10은 트립토판 , 티로신 , 페닐알라닌 , L-DOPA의 Na-독립+ 수송을 매개한다. [7]
참고 항목
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000112394 - 앙상블 , 2017년 5월 ^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000019838 - 앙상블 , 2017년 5월 ^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Entrez Gene: solute carrier family 16" . ^ Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H (May 2001). "Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters" . J. Biol. Chem . 276 (20): 17221–8. doi :10.1074/jbc.M009462200 . PMID 11278508 . ^ a b Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H (January 2002). "The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location". Genomics . 79 (1): 95–103. doi :10.1006/geno.2001.6678 . PMID 11827462 . 추가 읽기 Toure A, Morin L, Pineau C, et al. (2001). "Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling" . J. Biol. Chem . 276 (23): 20309–15. doi :10.1074/jbc.M011740200 . PMID 11278976 . Friesema EC, Jansen J, Jachtenberg JW, et al. (2008). "Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10" . Mol. Endocrinol . 22 (6): 1357–69. doi :10.1210/me.2007-0112 . PMC 5419535 . PMID 18337592 . Loubière LS, Vasilopoulou E, Bulmer JN, et al. (2010). "Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction" (PDF) . Placenta . 31 (4): 295–304. doi :10.1016/j.placenta.2010.01.013 . PMID 20167367 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 . Bröer S (2008). "Amino acid transport across mammalian intestinal and renal epithelia" . Physiol. Rev . 88 (1): 249–86. doi :10.1152/physrev.00018.2006 . PMID 18195088 . S2CID 1834804 . Park SY, Kim JK, Kim IJ, et al. (2005). "Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule". Arch. Pharm. Res . 28 (4): 421–32. doi :10.1007/BF02977671 . PMID 15918515 . S2CID 2139640 . Halestrap AP, Meredith D (2004). "The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond". Pflügers Arch . 447 (5): 619–28. doi :10.1007/s00424-003-1067-2 . PMID 12739169 . S2CID 15498611 .
그룹별
SLC1-10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11-20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21-30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31-40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41-48
(41): (42): (43): (44): (45): (46): (47): (48):