효소의 종류
세포질 티로신-단백질 키나아제 BMX 는 인간에서 BMX 유전자 에 의해 암호화된 효소 다.[5] [6]
함수 티로신 키나아제 는 투과체와 세포외 영역을 포함하는 수용체 분자 또는 세포내부에 위치한 비수용체 단백질이다.비수용자 TK의 한 계열에는 TEC , TXK , ITK , BTK 라는 유전자가 포함되어 있다. 이 모든 단백질은 드로소필라 SH3 와 SH2 도메인을 포함하고 있다.[6]
상호작용 BMX는 다음과 상호 작용하는 것으로 나타났다.
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000102010 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000031377 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K (December 1994). "BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2". Oncogene . 9 (12): 3683–8. PMID 7970727 . ^ a b "Entrez Gene: BMX BMX non-receptor tyrosine kinase" .^ Bagheri-Yarmand R, Mandal M, Taludker AH, Wang RA, Vadlamudi RK, Kung HJ, Kumar R (August 2001). "Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells" . J. Biol. Chem . 276 (31): 29403–9. doi :10.1074/jbc.M103129200 PMID 11382770 . ^ Chen R, Kim O, Li M, Xiong X, Guan JL, Kung HJ, Chen H, Shimizu Y, Qiu Y (May 2001). "Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain". Nat. Cell Biol . 3 (5): 439–44. doi :10.1038/35074500 . PMID 11331870 . S2CID 23449101 . ^ Jui HY, Tseng RJ, Wen X, Fang HI, Huang LM, Chen KY, Kung HJ, Ann DK, Shih HM (December 2000). "Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases" . J. Biol. Chem . 275 (52): 41124–32. doi :10.1074/jbc.M007772200 PMID 11013262 . ^ Yang J, Kim O, Wu J, Qiu Y (August 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking" . J. Biol. Chem . 277 (33): 30219–26. doi :10.1074/jbc.M111933200 PMID 11877430 . 추가 읽기 Robinson D, He F, Pretlow T, Kung HJ (1996). 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