예스1
YES1| 예스1 | |||||||||||||||||||||||||
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| 식별자 | |||||||||||||||||||||||||
| 별칭 | YES1, HsT441, P61-YES, 예, c-yes, YES proto-oncene 1, Src 계열 tyrosine kinase | ||||||||||||||||||||||||
| 외부 ID | OMIM: 164880 MGI: 99147 HomoloGene: 55900 GeneCard: YES1 | ||||||||||||||||||||||||
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| 직교체 | |||||||||||||||||||||||||
| 종 | 인간 | 마우스 | |||||||||||||||||||||||
| 엔트레스 | |||||||||||||||||||||||||
| 앙상블 | |||||||||||||||||||||||||
| 유니프로트 | |||||||||||||||||||||||||
| RefSeq(mRNA) | |||||||||||||||||||||||||
| RefSeq(단백질) | |||||||||||||||||||||||||
| 위치(UCSC) | Chr 18: 0.72 – 0.81Mb | Cr 5: 32.77 – 32.84Mb | |||||||||||||||||||||||
| PubMed 검색 | [3] | [4] | |||||||||||||||||||||||
| 위키다타 | |||||||||||||||||||||||||
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프로토온코제인 타이로신-단백질 키나아제 예스는 인간에서 YES1 유전자에 의해 암호화된 비수용체 타이로신 키나제다.[5][6]
이 유전자는 야마구치 육종 바이러스 유전자의 세포 호몰로그램이다.인코딩된 단백질은 tyrosine kinase 활성성을 가지며 src 계열에 속한다.이 유전자는 18번 염색체의 티미딜레이트 신타아제 유전자와 가까운 곳에 있으며, 22번 염색체에서 상응하는 유사유전자가 발견되었다.[6]
상호작용
YES1은 Janus kinase 2, [7]CTNND1, [8]RPL10[9] 및 Occludin과 상호작용하는 것으로 나타났다.[10]
참조
- ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000176105 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG00000014932 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Semba K, Yamanashi Y, Nishizawa M, Sukegawa J, Yoshida M, Sasaki M, Yamamoto T, Toyoshima K (Mar 1985). "Location of the c-yes gene on the human chromosome and its expression in various tissues". Science. 227 (4690): 1038–40. Bibcode:1985Sci...227.1038S. doi:10.1126/science.2983418. PMID 2983418.
- ^ a b "Entrez Gene: YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1".
- ^ Fuhrer, D K; Yang Y C (Jul 1996). "Complex formation of JAK2 with PP2A, P13K, and Yes in response to the hematopoietic cytokine interleukin-11". Biochem. Biophys. Res. Commun. 224 (2): 289–96. doi:10.1006/bbrc.1996.1023. ISSN 0006-291X. PMID 8702385.
- ^ Piedra, Jose; Miravet Susana; Castaño Julio; Pálmer Héctor G; Heisterkamp Nora; García de Herreros Antonio; Duñach Mireia (Apr 2003). "p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction" (PDF). Mol. Cell. Biol. 23 (7): 2287–97. doi:10.1128/MCB.23.7.2287-2297.2003. ISSN 0270-7306. PMC 150740. PMID 12640114.
- ^ Oh, Hyung Suk; Kwon Haeyoung; Sun Suk Kyun; Yang Chul-Hak (Sep 2002). "QM, a putative tumor suppressor, regulates proto-oncogene c-yes". J. Biol. Chem. 277 (39): 36489–98. doi:10.1074/jbc.M201859200. ISSN 0021-9258. PMID 12138090.
- ^ Chen, Yan-Hua; Lu Qun; Goodenough Daniel A; Jeansonne Beverly (Apr 2002). "Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells". Mol. Biol. Cell. 13 (4): 1227–37. doi:10.1091/mbc.01-08-0423. ISSN 1059-1524. PMC 102264. PMID 11950934.
추가 읽기
- Brickell PM (1992). "The p60c-src family of protein-tyrosine kinases: structure, regulation, and function". Critical Reviews in Oncogenesis. 3 (4): 401–46. PMID 1384720.
- Toyoshima K, Semba K, Nishizawa M, et al. (1988). "Nakahara memorial lecture. Non-receptor type protein-tyrosine kinases closely related to src and yes compose a multigene family". Int. Symp. Princess Takamatsu Cancer Res. Fund. 17: 11–20. PMID 3332005.
- Sudol M, Chen HI, Bougeret C, et al. (1995). "Characterization of a novel protein-binding module--the WW domain". FEBS Lett. 369 (1): 67–71. doi:10.1016/0014-5793(95)00550-S. PMID 7641887. S2CID 20664267.
- Summy JM, Sudol M, Eck MJ, et al. (2004). "Specificity in signaling by c-Yes". Front. Biosci. 8 (6): s185–205. doi:10.2741/1011. PMID 12456296.
- Cichowski K, McCormick F, Brugge JS (1992). "p21rasGAP association with Fyn, Lyn, and Yes in thrombin-activated platelets". J. Biol. Chem. 267 (8): 5025–8. doi:10.1016/S0021-9258(18)42721-4. PMID 1544885.
- Huang MM, Bolen JB, Barnwell JW, et al. (1991). "Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets". Proc. Natl. Acad. Sci. U.S.A. 88 (17): 7844–8. Bibcode:1991PNAS...88.7844H. doi:10.1073/pnas.88.17.7844. PMC 52400. PMID 1715582.
- Holtrich U, Bräuninger A, Strebhardt K, Rübsamen-Waigmann H (1992). "Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase". Proc. Natl. Acad. Sci. U.S.A. 88 (23): 10411–5. Bibcode:1991PNAS...8810411H. doi:10.1073/pnas.88.23.10411. PMC 52938. PMID 1720539.
- Krueger J, Zhao YH, Murphy D, Sudol M (1991). "Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis". Oncogene. 6 (6): 933–40. PMID 2067846.
- Zhao YH, Krueger JG, Sudol M (1991). "Expression of cellular-yes protein in mammalian tissues". Oncogene. 5 (11): 1629–35. PMID 2267131.
- Sukegawa J, Semba K, Yamanashi Y, et al. (1987). "Characterization of cDNA clones for the human c-yes gene". Mol. Cell. Biol. 7 (1): 41–7. doi:10.1128/MCB.7.1.41. PMC 365039. PMID 2436037.
- Bull HA, Brickell PM, Dowd PM (1994). "Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells". FEBS Lett. 351 (1): 41–4. doi:10.1016/0014-5793(94)00814-0. PMID 7521304. S2CID 45071719.
- Toshima J, Ohashi K, Iwashita S, Mizuno K (1995). "Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase". Biochem. Biophys. Res. Commun. 209 (2): 656–63. doi:10.1006/bbrc.1995.1549. PMID 7537495.
- Courtneidge SA, Dhand R, Pilat D, et al. (1993). "Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor". EMBO J. 12 (3): 943–50. doi:10.1002/j.1460-2075.1993.tb05735.x. PMC 413295. PMID 7681396.
- Mori S, Rönnstrand L, Yokote K, et al. (1993). "Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases". EMBO J. 12 (6): 2257–64. doi:10.1002/j.1460-2075.1993.tb05879.x. PMC 413454. PMID 7685273.
- Waltenberger J, Claesson-Welsh L, Siegbahn A, et al. (1994). "Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor". J. Biol. Chem. 269 (43): 26988–95. doi:10.1016/S0021-9258(18)47116-5. PMID 7929439.
- Silverman GA, Kuo WL, Taillon-Miller P, Gray JW (1993). "Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18". Genomics. 15 (2): 442–5. doi:10.1006/geno.1993.1086. PMID 8449516.
외부 링크
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