CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase는 인간에서 ST8SIA4 유전자 에 의해 암호화된 효소 다.[5] [6]
이 유전자에 의해 인코딩된 단백질은 신경세포 접착분자(NCAM1)의 접착 특성 모듈레이터인 폴리시알산 합성에 필요한 알파-2,8 연계 시알산의 폴리응축에 촉매 작용을 한다. 인코딩된 단백질은 글리코실전달효소 29과에 속하는 것으로 골기구에 존재할 수 있는 제2종 막단단백질이다. 다른 ISO 양식을 인코딩하는 두 개의 대본 변형이 이 유전자에 대해 발견되었다.[6]
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