알파-(1,3)-푸코실전달효소 는 인간에서 FUT7 유전자 에 의해 인코딩되는 효소 다.[5] [6] [7]
함수 시알릴 루이스 x 올리고당 결정체는 백혈구의 E-선택제(MIM 131210)와 P-선택제(MIM 173610) 매개 접착제용 백혈구 계수수용체의 필수 성분이다. 이 과두당 분자는 과립세포, 단세포, 자연 킬러 세포의 표면에 표시된다. 이들 셀렉틴에 대한 백혈구 접착제의 형성은 궁극적으로 백혈구가 혈관 트리를 떠나 림프 조직과 염증 부위에 포섭될 수 있도록 하는 과정의 초기 단계고 중요한 단계다. [OMIM에 의해 제공][7]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000180549 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000036587 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Natsuka S, Gersten KM, Zenita K, Kannagi R, Lowe JB (June 1994). "Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant" . The Journal of Biological Chemistry . 269 (24): 16789–94. doi :10.1016/S0021-9258(19)89461-9 PMID 8207002 . ^ Sasaki K, Kurata K, Funayama K, Nagata M, Watanabe E, Ohta S, Hanai N, Nishi T (May 1994). "Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes" . The Journal of Biological Chemistry . 269 (20): 14730–7. doi :10.1016/S0021-9258(17)36686-3 PMID 8182079 . ^ a b "Entrez Gene: FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)" .
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