IQCB1

IQCB1
식별자
에일리어스	IQCB1, NPHP5, PIQ, SLSN5, B1을 포함한 IQ 모티브
외부 ID	OMIM: 609237 MGI: 2443764 HomoloGene: 8766 GenCard: IQCB1
유전자 위치(인간)
크르.	3번 염색체(인간)
끝.	121,835,079 bp
유전자 위치(마우스)
크르.	16번 염색체(쥐)
끝.	36,693,083 bp
RNA발현패턴
	상단 표시 위치:
	난모세포; ; 단구; ; 췌장체; ; 아킬레스건; ; 직장; ; 기관지 상피 세포; ; 이차 난모세포; ; 우측 자궁관; ; 신경절 융기; ; 림프절;
	추가 참조 표현식 데이터
	; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	효소결합; GO:0001948 단백질 결합; 칼모듈린 결합;
셀룰러 컴포넌트	세포질; 미소관 조직 센터; 세포; 중심체; 광수용체 외측 세그먼트; 세포외 엑소좀; 세포골격; 섬유를 연결하는 광수용체; 중심; 핵소체; 미소관 세포골격; 세포간 교량; 유사분열 방추;
생물학적 과정	광수용체세포유지; 동물 장기 정체성 유지; 세포투영조직; 섬모조립체; 섬모 기저막 도킹;
	출처:아미고 / QuickGO
맞춤법
	9657
	320299
	ENSG00000173226
	ENSMUSG000022837
	문제 15051
	Q8BP00
	NM_001023570; NM_001023571; NM_001319107; NM_014642
	NM_177128
	NP_001018864; NP_001018865; NP_001306036
	NP_796102
	위키데이터
인간 보기/편집	마우스 표시/편집

IQ칼모듈린결합모티브함유단백질1은 IQCB1유전자에 ^[5]^[6]의해 인체 내에서 부호화되는 단백질이다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000173226 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000022837 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F (Feb 2005). "Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin". Nat Genet. 37 (3): 282–8. doi:10.1038/ng1520. PMID 15723066. S2CID 4972004.
^ "Entrez Gene: IQCB1 IQ motif containing B1".

추가 정보

Nomura N, Miyajima N, Sazuka T, et al. (1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
Nomura N, Miyajima N, Sazuka T, et al. (1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Mollet G, Salomon R, Gribouval O, et al. (2002). "The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin". Nat. Genet. 32 (2): 300–5. doi:10.1038/ng996. PMID 12244321. S2CID 24216974.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mollet G, Silbermann F, Delous M, et al. (2005). "Characterization of the nephrocystin/nephrocystin-4 complex and subcellular localization of nephrocystin-4 to primary cilia and centrosomes". Hum. Mol. Genet. 14 (5): 645–56. doi:10.1093/hmg/ddi061. PMID 15661758.
le Maire A, Weber T, Saunier S, et al. (2006). "Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis". Proteins. 59 (2): 347–55. doi:10.1002/prot.20344. PMID 15723349. S2CID 37333782.
Luo X, He Q, Huang Y, Sheikh MS (2006). "Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers". Cancer Res. 65 (23): 10725–33. doi:10.1158/0008-5472.CAN-05-1132. PMID 16322217.

인간 염색체 3번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000173226 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000022837 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15723066-5] Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F (Feb 2005). "Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin". Nat Genet. 37 (3): 282–8. doi:10.1038/ng1520. PMID 15723066. S2CID 4972004.

[entrez-6] "Entrez Gene: IQCB1 IQ motif containing B1".

[1]

[2]

[3]

[4]

[5]

[6]

v t 섬모단백질
네프로시스틴	NPHP1 인비 NPHP3 NPHP4 IQCB1 CEP290 GLIS2 RPGRIP1L
기초체	BB썸 BBS1 BBS2 BBS4 BBS5 BBS7 TTC8 BBS9 보호자 MKKS BBS10 BBS12 다른. ARL6 트림32 ALMS1 CC2D2A CEP290 MKS1 RPGRIP1L OFD1 AHI1 인비 NPHP4 NEK8 NPHP1
실리아	연결 섬모 LCA5 RP1 RPGR RPGRIP1 툴프1 일차 섬모 ARL13B INPP5E IQCB1 PKHD1 PKD1 PKD2 TMEM67
다이닌	외다인 팔 DNAH5 DNAI2 DNAL1 축삭암 DNAH11 DNAI1
레이디얼 스포크	RSPH1 RSPH3 RSPH4A RSPH6A RSPH9 RSPH10B
다른.	세포질 전교조 핵 GLIS2 편모내 수송 IFT80 다른. AHI1 ARL13B 브릭스3 INPP5E KIF3A LRRC50 SDCCAG8 TMEM216 TXNDC3
참고 항목: 섬모증

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IQCB1

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