SPTLC1이라고 도 알려진 긴 사슬 염기서브유닛 1인 세린 팔미토일전달효소(Serine palmitoyl transferase)는 SPTLC1 [5] [6] 단백질 이다.
두 개의 다른 서브유닛으로 구성된 세린 팔미토일전달효소 는 스핑고리피드 생합성의 초기 효소이다.L-세린 과 팔미토일 CoA 를 피리독살 5'-인산 을 보조 인자로 하는 3-옥소스핑가닌으로 전환한다.이 유전자의 산물은 세린팔미토일전달효소의 긴 사슬 염기서브유닛1이다. 이 유전자 의 돌연변이는 유전성 감각 신경증 타입 1 환자에서 확인되었다. 다른 아이소폼을 코드하는 대체 스플라이스 변종이 [5]
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