핵수용체 공동활성화기 1

NCOA1
사용 가능한 구조물
PDB	직교 검색: PDBe RCSB
PDB ID 코드 목록
	1FM6, 1FM9, 1K74, 1K7L, 1KV6, 1K4W, 1N4H, 1NQ7, 1NRL, 1P8D, 1PZL, 1RDT, 1TFC, 1U3R, 1U3S, 1X76, 1XIU, 1XV9, 1XVP, 1YY4, 1ZAF, 2A3I, 2C52, 2FVJ, 2GTK, 2HBH, 2HC4, 2HCD, 2HFP, 2NPA, 2NV7, 2P54, 2PRG, 3BEJ, 3BQD, 3CTB, 3CWD, 3DCT, 3DCU, 3DR1, 3ET1, 3ET3, 3FEI, 3FEJ, 3FUR, 3FXV, 3G8I, 3G9E, 3GYT, 3GYU, 3H0A, 3HC5, 3HC6, 3HVL, 3IPQ, 3IPS, 3IPU, 3KMR, 3LMP, 3OKH, 3OKI, 3OLF, 3OLL, 3OLS, 3OMK, 3OMM, 3OMO, 3OMP, 3OMQ, 3OOF, 3OOK, 3P88, 3P89, 3QT0, 3RUT, 3RUU, 3RVF, 3S9S, 3T03, 3UU7, 3UUA, 3UUD, 3V9Y, 3VN2, 4DK7, 4DK8, 4DM6, 4DM8, 4DQM, 4F9M, 4FGY, 4G1D, 4G1Y, 4G1Z, 4G20, 4G21, 4G2H, 4HEE, 4J5X, 4JYG, 4JYH, 4JYI, 4MG5, 4MG6, 4MG7, 4MG8, 4MG9, 4MGA, 4MGB, 4MGC, 4MGD, 4TUZ, 4TV1, 5AVI, 5AVL, 4Y29, 4RUJ, 4RUP, 5A86, 5E7V, 4UDB, 4UDA, 5AZT, 5HJS
식별자
별칭	NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74, 핵수용체 공동활성화기 1
외부 ID	OMIM: 602691 MGI: 1276523 호몰로진: 7859 GeneCard: NCOA1
유전자 위치(인간)
쳇.	염색체 2 (인간)
끝	24,770,702 bp
유전자 위치(마우스)
쳇.	12번 염색체(쥐)
끝	4,477,190 bp
RNA 표현 패턴
	표현된 상단
	프로센스팔론; ; 결장의; ; 신피질; ; 중간 측두회; ; 위두근; ; 중전두회; ; 입자핵; ; 뱃속;
	추가 참조 표현식 데이터
	; ; ; ;
	추가 참조 표현식 데이터
유전자 온톨로지
분자함수	전이효소 활동; DNA 결합; GO:0001105 전사 공동활성화기 활동; 단백질 조광 활성; 단백질 N단자 결합; 전사 계수 바인딩; 염색질 제본; 히스톤 아세틸전달효소 활동; GO:0001948 단백질 결합; 안드로겐 수용체 결합; 효소 결합; 아킬전달효소 활동; 핵수용체 공동활성화기 활동; 아릴 탄화수소 수용체 결합; 핵수용체 결합; 에스트로겐 수용체 결합; GO:0001200, GO:0001133, GO:0001201 DNA 결합 전사 계수 활성, RNA 중합효소 II 고유; 프로게스테론 수용체 결합; 레티노산 수용체 결합; GO:0032403 단백질 함유 복합 결합; 레티노이드 X 수용체 결합;
셀룰러 컴포넌트	핵의; 핵종의; 시토솔; 플라즈마 막; 단백질 함유 복합체; 세포질; 뉴런 투영법;
생물학적 과정	안드로겐 수용체 신호 경로; RNA 생합성 공정의 조절; 전사 규정, DNA-템플링; Tyroglobulin triodoshyronine에 대한 세포 반응; 약물에 대한 세포 반응의 조절; 전사, DNA-템플릿; 전사의 양성적 조절, DNA-템플링; 미로층 형태생성; 뉴런 분화의 긍정적인 조절; 담즙산과 담즙염 수송; 양세포 과정에 대한 양성 규제; 히스톤 H4 아세틸화; 갑상선 호르몬 매개 신호 경로의 조절; RNA 중합효소 II에 의한 전사의 양성 조절; 세포내 수용체 신호 경로; 갈락토오스(galactose)에 의한 RNA 중합효소 II 촉진제로부터의 전사의 양성 조절; 지질 대사 과정 조절; RNA 중합효소 II에 의한 전사; 호르몬 자극에 대한 세포 반응; 젖먹이; 남성 생식기 발달; 호르몬에 대한 반응; 소뇌 발달; 해마 개발; 시상하부 발달; 대뇌피질 발달; 에스트라디올에 대한 반응; 레티노산 반응; 프로게스테론 대응; 제철의 순환; 여성 수용성에 대한 긍정적인 규제; 수컷 짝짓기 행동;
	출처:아미고 / 퀵고
직교체
	8648
	17977
	ENSG00000084676
	ENSMUSG00000020647
	Q15788
	P70365
NM_003743; NM_147223; NM_147233; NM_001362950; NM_001362952;
	NM_001362954; NM_001362955
	NM_010881
NP_003734; NP_671756; NP_671766; NP_001349879; NP_001349881;
	NP_001349883; NP_001349884
	NP_035011
	위키다타
인간 보기/편집	마우스 보기/편집

핵수용체 공동활성화제 1(NCOA1)은 여러 개의 핵수용체 상호작용 영역과 내인성 히스톤 아세틸전달효소 활성을 포함하는 전사적 코로게이터 단백질이다. NCOA1은 리간드 활성 핵 수용체에 의해 DNA 촉진 현장에 채용된다. 다시, NCOA1은 히스톤을 아틸레이트하여 다운스트림 DNA를 전사하기 쉽게 만든다. 따라서, NCOA1은 DNA 표현의 상향 조정에서 핵 수용체를 지원한다.^[5]^[6]

NCOA1은 스테로이드 수용체 공동활성화제-1(SRC-1)이라고도 불린다.

상호작용

핵수용체 공동활성화기 1은 기본적인 나선-루프-헬릭스(bHLH) 영역을 가지며, 다음과 상호작용하는 것으로 나타났다.

참조

^ ^a ^b ^c GRCh38: 앙상블 릴리스 89: ENSG000084676 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리스 89: ENSMUSG000020647 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Oñate SA, Tsai SY, Tsai MJ, O'Malley BW (1995). "Sequence and characterization of a coactivator for the steroid hormone receptor superfamily". Science. 270 (5240): 1354–1357. Bibcode:1995Sci...270.1354O. doi:10.1126/science.270.5240.1354. PMID 7481822. S2CID 28749162.
^ Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW (1998). "The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors". Journal of Biological Chemistry. 273 (20): 12101–12108. doi:10.1074/jbc.273.20.12101. PMID 9575154.
^ Masiello D, Chen SY, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, Balk SP (Oct 2004). "Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells". Molecular Endocrinology. 18 (10): 2388–2401. doi:10.1210/me.2003-0436. PMID 15256534.
^ Ueda T, Mawji NR, Bruchovsky N, Sadar MD (Oct 2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells". Journal of Biological Chemistry. 277 (41): 38087–38094. doi:10.1074/jbc.M203313200. PMID 12163482.
^ Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG (Dec 1999). "The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1". Molecular and Cellular Biology. 19 (12): 8383–8392. doi:10.1128/mcb.19.12.8383. PMC 84931. PMID 10567563.
^ ^a ^b ^c Lee SK, Na SY, Jung SY, Choi JE, Jhun BH, Cheong J, Meltzer PS, Lee YC, Lee JW (Jun 2000). "Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2". Molecular Endocrinology. 14 (6): 915–925. doi:10.1210/mend.14.6.0471. PMID 10847592.
^ ^a ^b Lee SK, Kim HJ, Na SY, Kim TS, Choi HS, Im SY, Lee JW (Jul 1998). "Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits". Journal of Biological Chemistry. 273 (27): 16651–16654. doi:10.1074/jbc.273.27.16651. PMID 9642216.
^ Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW (Nov 1999). "A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo". Journal of Biological Chemistry. 274 (48): 34283–34293. doi:10.1074/jbc.274.48.34283. PMID 10567404.
^ Tzortzakaki E, Spilianakis C, Zika E, Kretsovali A, Papamatheakis J (Dec 2003). "Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways". Molecular Endocrinology. 17 (12): 2509–2518. doi:10.1210/me.2002-0439. PMID 12933903.
^ ^a ^b Sheppard HM, Harries JC, Hussain S, Bevan C, Heery DM (Jan 2001). "Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1". Molecular and Cellular Biology. 21 (1): 39–50. doi:10.1128/MCB.21.1.39-50.2001. PMC 86566. PMID 11113179.
^ Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW (May 2002). "Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase". Molecular and Cellular Biology. 22 (10): 3549–3461. doi:10.1128/MCB.22.10.3549-3561.2002. PMC 133790. PMID 11971985.
^ Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ, Bernards R (Nov 1998). "Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1". Genes & Development. 12 (22): 3488–3498. doi:10.1101/gad.12.22.3488. PMC 317237. PMID 9832502.
^ ^a ^b ^c Watanabe M, Yanagisawa J, Kitagawa H, Takeyama K, Ogawa S, Arao Y, Suzawa M, Kobayashi Y, Yano T, Yoshikawa H, Masuhiro Y, Kato S (Mar 2001). "A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA". EMBO Journal. 20 (6): 1341–1352. doi:10.1093/emboj/20.6.1341. PMC 145523. PMID 11250900.
^ DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M (Oct 2000). "BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation". Molecular and Cellular Biology. 20 (20): 7541–7549. doi:10.1128/MCB.20.20.7541-7549.2000. PMC 86306. PMID 11003650.
^ Kalkhoven E, Valentine JE, Heery DM, Parker MG (Jan 1998). "Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor". EMBO Journal. 17 (1): 232–243. doi:10.1093/emboj/17.1.232. PMC 1170374. PMID 9427757.
^ Kang YK, Guermah M, Yuan CX, Roeder RG (Mar 2002). "The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro". Proceedings of the National Academy of Sciences, USA. 99 (5): 2642–2647. Bibcode:2002PNAS...99.2642K. doi:10.1073/pnas.261715899. PMC 122401. PMID 11867769.
^ Zilliacus J, Holter E, Wakui H, Tazawa H, Treuter E, Gustafsson JA (Apr 2001). "Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140". Molecular Endocrinology. 15 (4): 501–511. doi:10.1210/mend.15.4.0624. PMID 11266503.
^ Kucera T, Waltner-Law M, Scott DK, Prasad R, Granner DK (Jul 2002). "A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1". Journal of Biological Chemistry. 277 (29): 26098–260102. doi:10.1074/jbc.M204013200. PMID 12118039.
^ Na SY, Lee SK, Han SJ, Choi HS, Im SY, Lee JW (May 1998). "Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations". Journal of Biological Chemistry. 273 (18): 10831–10834. doi:10.1074/jbc.273.18.10831. PMID 9556555.
^ Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW (Sep 1997). "Steroid receptor coactivator-1 is a histone acetyltransferase". Nature. 389 (6647): 194–198. Bibcode:1997Natur.389..194S. doi:10.1038/38304. PMID 9296499. S2CID 4404530.
^ Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM (Nov 1999). "Activation of PPARgamma coactivator-1 through transcription factor docking". Science. 286 (5443): 1368–1371. doi:10.1126/science.286.5443.1368. PMID 10558993.
^ Dowell P, Ishmael JE, Avram D, Peterson VJ, Nevrivy DJ, Leid M (Dec 1997). "p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha". Journal of Biological Chemistry. 272 (52): 33435–33443. doi:10.1074/jbc.272.52.33435. PMID 9407140.
^ Treuter E, Albrektsen T, Johansson L, Leers J, Gustafsson JA (Jun 1998). "A regulatory role for RIP140 in nuclear receptor activation". Molecular Endocrinology. 12 (6): 864–881. doi:10.1210/mend.12.6.0123. PMID 9626662.
^ Zhang C, Baudino TA, Dowd DR, Tokumaru H, Wang W, MacDonald PN (Nov 2001). "Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription". Journal of Biological Chemistry. 276 (44): 40614–40620. doi:10.1074/jbc.M106263200. PMID 11514567.
^ Giraud S, Bienvenu F, Avril S, Gascan H, Heery DM, Coqueret O (Mar 2002). "Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a". Journal of Biological Chemistry. 277 (10): 8004–811. doi:10.1074/jbc.M111486200. PMID 11773079.
^ Litterst CM, Pfitzner E (Dec 2001). "Transcriptional activation by STAT6 requires the direct interaction with NCoA-1". Journal of Biological Chemistry. 276 (49): 45713–45721. doi:10.1074/jbc.M108132200. PMID 11574547.
^ Litterst CM, Pfitzner E (Sep 2002). "An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1". Journal of Biological Chemistry. 277 (39): 36052–36060. doi:10.1074/jbc.M203556200. PMID 12138096.
^ Kim HJ, Yi JY, Sung HS, Moore DD, Jhun BH, Lee YC, Lee JW (Sep 1999). "Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation". Molecular and Cellular Biology. 19 (9): 6323–6332. doi:10.1128/mcb.19.9.6323. PMC 84603. PMID 10454579.
^ Liu Y, Takeshita A, Misiti S, Chin WW, Yen PM (Oct 1998). "Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors". Endocrinology. 139 (10): 4197–4204. doi:10.1210/endo.139.10.6218. PMID 9751500.
^ Jeyakumar M, Tanen MR, Bagchi MK (Jun 1997). "Analysis of the functional role of steroid receptor coactivator-1 in ligand-induced transactivation by thyroid hormone receptor". Molecular Endocrinology. 11 (6): 755–767. doi:10.1210/mend.11.6.0003. PMID 9171239.

외부 링크

미국 국립 의학 도서관(MSH)의 핵 수용체 공동 활성제 1
누르사 C89

추가 읽기

Qi C, Zhu Y, Reddy JK (2001). "Peroxisome proliferator-activated receptors, coactivators, and downstream targets". Cell Biochemistry and Biophysics. 32. Spring (1–3): 187–204. doi:10.1385/cbb:32:1-3:187. PMID 11330046. S2CID 31795393.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리스 89: ENSG000084676 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리스 89: ENSMUSG000020647 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Onate_1995-5] Oñate SA, Tsai SY, Tsai MJ, O'Malley BW (1995). "Sequence and characterization of a coactivator for the steroid hormone receptor superfamily". Science. 270 (5240): 1354–1357. Bibcode:1995Sci...270.1354O. doi:10.1126/science.270.5240.1354. PMID 7481822. S2CID 28749162.

[Onate_1998-6] Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW (1998). "The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors". Journal of Biological Chemistry. 273 (20): 12101–12108. doi:10.1074/jbc.273.20.12101. PMID 9575154.

[pmid15256534-7] Masiello D, Chen SY, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, Balk SP (Oct 2004). "Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells". Molecular Endocrinology. 18 (10): 2388–2401. doi:10.1210/me.2003-0436. PMID 15256534.

[pmid12163482-8] Ueda T, Mawji NR, Bruchovsky N, Sadar MD (Oct 2002). "Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells". Journal of Biological Chemistry. 277 (41): 38087–38094. doi:10.1074/jbc.M203313200. PMID 12163482.

[pmid10567563-9] Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG (Dec 1999). "The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1". Molecular and Cellular Biology. 19 (12): 8383–8392. doi:10.1128/mcb.19.12.8383. PMC 84931. PMID 10567563.

[pmid10847592-10] Lee SK, Na SY, Jung SY, Choi JE, Jhun BH, Cheong J, Meltzer PS, Lee YC, Lee JW (Jun 2000). "Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2". Molecular Endocrinology. 14 (6): 915–925. doi:10.1210/mend.14.6.0471. PMID 10847592.

[pmid9642216-11] Lee SK, Kim HJ, Na SY, Kim TS, Choi HS, Im SY, Lee JW (Jul 1998). "Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits". Journal of Biological Chemistry. 273 (27): 16651–16654. doi:10.1074/jbc.273.27.16651. PMID 9642216.

[pmid10567404-12] Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW (Nov 1999). "A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo". Journal of Biological Chemistry. 274 (48): 34283–34293. doi:10.1074/jbc.274.48.34283. PMID 10567404.

[pmid12933903-13] Tzortzakaki E, Spilianakis C, Zika E, Kretsovali A, Papamatheakis J (Dec 2003). "Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways". Molecular Endocrinology. 17 (12): 2509–2518. doi:10.1210/me.2002-0439. PMID 12933903.

[pmid11113179-14] Sheppard HM, Harries JC, Hussain S, Bevan C, Heery DM (Jan 2001). "Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1". Molecular and Cellular Biology. 21 (1): 39–50. doi:10.1128/MCB.21.1.39-50.2001. PMC 86566. PMID 11113179.

[pmid11971985-15] Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW (May 2002). "Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase". Molecular and Cellular Biology. 22 (10): 3549–3461. doi:10.1128/MCB.22.10.3549-3561.2002. PMC 133790. PMID 11971985.

[pmid9832502-16] Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ, Bernards R (Nov 1998). "Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1". Genes & Development. 12 (22): 3488–3498. doi:10.1101/gad.12.22.3488. PMC 317237. PMID 9832502.

[pmid11250900-17] Watanabe M, Yanagisawa J, Kitagawa H, Takeyama K, Ogawa S, Arao Y, Suzawa M, Kobayashi Y, Yano T, Yoshikawa H, Masuhiro Y, Kato S (Mar 2001). "A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA". EMBO Journal. 20 (6): 1341–1352. doi:10.1093/emboj/20.6.1341. PMC 145523. PMID 11250900.

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v t 전사 코어글레이터
공동활성화기	ARA(54, 55, 70) BCAS3 CARM1 p300-CBP(EP300, CREBBP) CRTC(1, 2, 3) DRIP/TRAP (MED1 Drip205/Trap220) MN1 PCAF PNRC(1, 2) PPARGC(1A, 1B) TGFB1I1 NCOA1(SRC-1) NCOA2(GRIP1/SRC-2/TIF2) NCOA3(AIB/SRC-3/TRAM-1) NCOA4(ARA70) NCOA5(CIA) NCOA6(RAP250) NCOA7(ERAP140)
코어프레스기	CTBP(1, 2) 털이 없는 호몰로지 LCOR NRIP1 (RIP140) 펠프-1 RCOR1 Rb 신3A 신3B 삼부 모티브 계열트림(24, 28, 33) NCOR1 NCOR2(SMRT)
ATP 의존적 리모델링 요인	크로마틴 구조 리모델링(RSC SWI/SNF

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