가능성 이 있는 ATP 의존성 RNA 헬리케이스 DDX17( p72)은 DDX17 유전자에 [5] [6] 효소 이다.
기능. 보존 모티브 Asp-Glu-Ala-Asp(DEAD)를 특징으로 하는 DEAD 박스 단백질은 추정 RNA 헬리케이스이다. 이들은 번역 개시, 핵 및 미토콘드리아 스플라이싱, 리보솜 및 스플라이세솜 조립과 같은 RNA 2차 구조의 변화를 수반하는 많은 세포 과정에 관여한다. 그들의 분포 패턴에 근거하여, 이 과의 일부 구성원들은 배아 발생, 정자 형성, 그리고 세포 성장과 분열에 관여하는 것으로 여겨진다. 이 유전자는 dsDNA가 아닌 다양한 RNA 종에 의해 활성화된 ATP 효소인 DEAD 박스 단백질을 암호화합니다. 이 단백질과 DDX5 유전자에 의해 암호화된 단백질은 DEAD 박스 패밀리의 다른 어떤 구성원보다 서로 더 밀접하게 관련되어 있습니다. 이 유전자의 대체 스플라이싱은 다른 아이소폼을 코드하는 2개의 전사 변이를 생성하며, 긴 전사 역시 비 AUG(CUG) 시작 [6]
상호 작용 DDX17은 다음 제품과 상호 작용하는 것 으로 나타났습니다.
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