FYVE, RhoGEF 및 PH 도메인 함유 단백질 4는 FGD4 [5] [6] 단백질 이다.
레퍼런스 추가 정보 Obaishi H, Nakanishi H, Mandai K, et al. (1998). "Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase" . J. Biol. Chem . 273 (30): 18697–700. doi :10.1074/jbc.273.30.18697 PMID 9668039 . Ikeda W, Nakanishi H, Tanaka Y, et al. (2001). "Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation" . Oncogene . 20 (27): 3457–63. doi :10.1038/sj.onc.1204463 PMID 11429692 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Chen XM, Splinter PL, Tietz PS, et al. (2004). "Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42" . J. Biol. Chem . 279 (30): 31671–8. doi :10.1074/jbc.M401592200 PMID 15133042 . De Sandre-Giovannoli A, Delague V, Hamadouche T, et al. (2006). "Homozygosity mapping of autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy (CMT4H) to a novel locus on chromosome 12p11.21-q13.11" . J. Med. Genet . 42 (3): 260–5. doi :10.1136/jmg.2004.024364 . PMC 1736004 PMID 15744041 . Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H" . Am. J. Hum. Genet . 81 (1): 1–16. doi :10.1086/518428 . PMC 1950914 PMID 17564959 . Stendel C, Roos A, Deconinck T, et al. (2007). "Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4" . Am. J. Hum. Genet . 81 (1): 158–64. doi :10.1086/518770 . PMC 1950925 PMID 17564972 .
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