FYVE, RhoGEF 및 PH 도메인 함유 단백질 2(FGD2)는 아연 핑거 FYVE4 (ZFYVE4)라고도 하며 FGD2 [5] 단백질 이다.
패밀리를 포함하는 FYVE , RhoGEF 및 PH 도메인 의 구성원입니다.
레퍼런스 추가 정보 Salehi AH, Xanthoudakis S, Barker PA (2002). "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway" . J. Biol. Chem . 277 (50): 48043–50. doi :10.1074/jbc.M205324200 PMID 12376548 . Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6" . Nature . 425 (6960): 805–11. Bibcode :2003Natur.425..805M . doi :10.1038/nature02055 PMID 14574404 . Hattori A, Okumura K, Nagase T, et al. (2000). "Characterization of long cDNA clones from human adult spleen" . DNA Res . 7 (6): 357–66. doi :10.1093/dnares/7.6.357 PMID 11214971 . Pasteris NG, Gorski JL (1999). "Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues". Genomics . 60 (1): 57–66. doi :10.1006/geno.1999.5903 . PMID 10458911 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Harrington AW, Kim JY, Yoon SO (2002). "Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis" . J. Neurosci . 22 (1): 156–66. doi :10.1523/JNEUROSCI.22-01-00156.2002 . PMC 6757583 PMID 11756498 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Rabizadeh S, Bredesen DE (2003). "Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR)". Cytokine Growth Factor Rev . 14 (3–4): 225–39. doi :10.1016/S1359-6101(03)00018-2 . PMID 12787561 . Huber C, Mårtensson A, Bokoch GM, et al. (2008). "FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles" . J. Biol. Chem . 283 (49): 34002–12. doi :10.1074/jbc.M803957200 PMC 2590680 PMID 18838382 . Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H" . Am. J. Hum. Genet . 81 (1): 1–16. doi :10.1086/518428 . PMC 1950914 PMID 17564959 .
