염색체 관련 폴리펩타이드 C (CAP-C) 또는 XCAP-C 호몰로그램 으로도 알려진 염색체 단백질 4 (SMC-4)의 구조적 유지보수 는 인간에서 SMC4 유전자 에 의해 암호화된 단백질 이다.[5] [6] [7] SMC-4는 염색체 응축에 관련된 큰 단백질 복합체인 콘덴서 I와 II의 핵심 부속품이다.
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000113810 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000000349 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Schmiesing JA, Ball AR Jr, Gregson HC, Alderton JM, Zhou S, Yokomori K (Nov 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics" . Proc Natl Acad Sci U S A . 95 (22): 12906–11. Bibcode :1998PNAS...9512906S . doi :10.1073/pnas.95.22.12906 PMC 23650 PMID 9789013 . ^ Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y (Jun 1999). "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family" . J Hum Genet . 44 (3): 197–202. doi :10.1007/s100380050142 PMID 10319587 . ^ "Entrez Gene: SMC4 structural maintenance of chromosomes 4" . 추가 읽기 Hirano T (2002). "The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair" . Genes Dev . 16 (4): 399–414. doi :10.1101/gad.955102 PMID 11850403 . Ball Jr AR, Yokomori K (2001). "The structural maintenance of chromosomes (SMC) family of proteins in mammals". Chromosome Res . 9 (2): 85–96. doi :10.1023/A:1009287518015 . PMID 11321372 . S2CID 23761326 . Ham MF, Takakuwa T, Rahadiani N, et al. (2007). "Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma". Cancer Sci . 98 (7): 1041–7. doi :10.1111/j.1349-7006.2007.00500.x . PMID 17488335 . S2CID 25888221 . Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle" . Proc. Natl. Acad. Sci. U.S.A . 103 (14): 5391–6. Bibcode :2006PNAS..103.5391N . doi :10.1073/pnas.0507066103 PMC 1459365 PMID 16565220 . Geiman TM, Sankpal UT, Robertson AK, et al. (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery" . Nucleic Acids Res . 32 (9): 2716–29. doi :10.1093/nar/gkh589 . PMC 419596 PMID 15148359 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Kimura K, Cuvier O, Hirano T (2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts" . J. Biol. Chem . 276 (8): 5417–20. doi :10.1074/jbc.C000873200 PMID 11136719 . Schmiesing JA, Gregson HC, Zhou S, Yokomori K (2000). "A Human Condensin Complex Containing hCAP-C–hCAP-E and CNAP1, a Homolog of Xenopus XCAP-D2, Colocalizes with Phosphorylated Histone H3 during the Early Stage of Mitotic Chromosome Condensation" . Mol. Cell. Biol . 20 (18): 6996–7006. doi :10.1128/MCB.20.18.6996-7006.2000 . PMC 88774 PMID 10958694 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 .
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