호모사피엔스 종의 단백질 코딩 유전자
염색체 관련 단백질 E (CAP-E)로도 알려진 염색체 단백질 2 (SMC-2)의 구조적 유지 (Structural maintenance)는 인간에서 SMC2 유전자 에 의해 인코딩 되는 단백질이다.[5] [6]
SMC-2는 염색체 응축에 관련된 큰 단백질 복합체인 콘덴서 I과 II의 하위 단위다.
상호작용 SMC2는 DNMT3B 와 상호작용 하는 것으로 나타났다.[7]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000136824 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000028312 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Schmiesing JA, Ball AR, Gregson HC, Alderton JM, Zhou S, Yokomori K (Oct 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics" . Proceedings of the National Academy of Sciences of the United States of America . 95 (22): 12906–11. Bibcode :1998PNAS...9512906S . doi :10.1073/pnas.95.22.12906 PMC 23650 PMID 9789013 . ^ "Entrez Gene: SMC2 structural maintenance of chromosomes 2" .^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery" . Nucleic Acids Research . 32 (9): 2716–29. doi :10.1093/nar/gkh589 . PMC 419596 PMID 15148359 .
추가 읽기 Ham MF, Takakuwa T, Rahadiani N, Tresnasari K, Nakajima H, Aozasa K (Jul 2007). "Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma". Cancer Science . 98 (7): 1041–7. doi :10.1111/j.1349-7006.2007.00500.x . PMID 17488335 . S2CID 25888221 . Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Molecular Systems Biology . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 . Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (Jan 2005). "Nucleolar proteome dynamics". Nature . 433 (7021): 77–83. Bibcode :2005Natur.433...77A . doi :10.1038/nature03207 . PMID 15635413 . S2CID 4344740 . Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery" . Nucleic Acids Research . 32 (9): 2716–29. doi :10.1093/nar/gkh589 . PMC 419596 PMID 15148359 . Przewloka MR, Pardington PE, Yannone SM, Chen DJ, Cary RB (Feb 2003). "In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex" . Molecular Biology of the Cell . 14 (2): 685–97. doi :10.1091/mbc.E01-11-0117 . PMC 150001 PMID 12589063 . Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts" . The Journal of Biological Chemistry . 276 (8): 5417–20. doi :10.1074/jbc.C000873200 PMID 11136719 . Schmiesing JA, Gregson HC, Zhou S, Yokomori K (Sep 2000). "A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation" . Molecular and Cellular Biology . 20 (18): 6996–7006. doi :10.1128/MCB.20.18.6996-7006.2000 . PMC 88774 PMID 10958694 . 외부 링크 PDBe-KB 는 염색체 단백질 2의 인간 구조 유지관리를 위해 PDB에서 이용할 수 있는 모든 구조 정보의 개요를 제공한다.PDBe-KB 는 염색체 단백질 2의 마우스 구조 유지관리를 위해 PDB에서 이용할 수 있는 모든 구조 정보의 개요를 제공한다.
