TNP1

TNP1
식별자
별칭	TNP1, TP1, 전환 단백질 1
외부 ID	OMIM: 190231 MGI: 9874 HomoloGene: 136517 GeneCard: TNP1
유전자 위치(인간)
쳇.	염색체 2 (인간)
끝	216,860,064 bp
유전자 위치(마우스)
쳇.	1번 염색체(쥐)
끝	73,055,068 bp
RNA 표현 패턴
	표현된 상단
	고환; ; 소뇌 진피; ; 전립선의; ; 척추 갱년기; ; 대뇌피질;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 온톨로지
분자함수	DNA 결합; GO:0001948 단백질 결합;
셀룰러 컴포넌트	남성 생식 세포핵; 뉴클레오솜의; 염색체; 핵의;
생물학적 과정	다세포 유기체 개발; 단일 가닥 파단 수리; 날염된 정자 운동성; 염색질 리모델링; 수정, 염색체 단백질의 교환; 정자핵 분화; 세포 분화; 정자핵 신장; 핵 분해; 전사의 음성적 조절, DNA-템플링; 성적 생식; 정자생식; 정자 발달; 단백질 처리의 양성 규제; 정조세포, 염색체 단백질의 교환;
	출처:아미고 / 퀵고
직교체
	7141
	21958
	ENSG00000118245
	ENSMUSG00000026182
	P09430
	P10856
	NM_003284
	NM_009407
	NP_003275
	NP_033433
	위키다타
인간 보기/편집	마우스 보기/편집

정조세포 핵전환 단백질 1은 인간에서 TNP1 유전자에 의해 암호화된 단백질이다.^[5]^[6]

참조

^ ^a ^b ^c GRCh38: 앙상블 릴리스 89: ENSG00000118245 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리스 89: ENSMUSG000026182 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Luerssen H, Mattei MG, Schroter M, Grzeschik KH, Adham IM, Engel W (Jan 1991). "Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2". Genomics. 8 (2): 324–30. doi:10.1016/0888-7543(90)90289-7. PMID 2249851.
^ "Entrez Gene: TNP1 transition protein 1 (during histone to protamine replacement)".

추가 읽기

Meistrich ML, Mohapatra B, Shirley CR, Zhao M (2004). "Roles of transition nuclear proteins in spermiogenesis". Chromosoma. 111 (8): 483–8. doi:10.1007/s00412-002-0227-z. PMID 12743712. S2CID 28866607.
Chirat F, Martinage A, Briand G, et al. (1991). "Nuclear transition protein 1 from ram elongating spermatids. Mass spectrometric characterization, primary structure and phosphorylation sites of two variants" (PDF). Eur. J. Biochem. 198 (1): 13–20. doi:10.1111/j.1432-1033.1991.tb15980.x. PMID 2040274.
Baskaran R, Rao MR (1991). "Interaction of spermatid-specific protein TP2 with nucleic acids, in vitro. A comparative study with TP1". J. Biol. Chem. 265 (34): 21039–47. doi:10.1016/S0021-9258(17)45324-5. PMID 2250010.
Kleene KC, Borzorgzadeh A, Flynn JF, et al. (1988). "Nucleotide sequence of a cDNA clone encoding mouse transition protein 1". Biochim. Biophys. Acta. 950 (2): 215–20. doi:10.1016/0167-4781(88)90013-9. PMID 3382664.
Luerssen H, Hoyer-Fender S, Engel W (1988). "The nucleotide sequence of human transition protein 1 cDNA". Nucleic Acids Res. 16 (15): 7723. doi:10.1093/nar/16.15.7723. PMC 338445. PMID 3412903.
Akama K, Kojima S, Nakano M, et al. (1994). "The amino acid sequence and phosphorylation sites of a boar transition protein 1". Biochem. Mol. Biol. Int. 32 (2): 349–57. PMID 8019440.
Steger K, Klonisch T, Gavenis K, et al. (1999). "Expression of mRNA and protein of nucleoproteins during human spermiogenesis". Mol. Hum. Reprod. 4 (10): 939–45. doi:10.1093/molehr/4.10.939. PMID 9809674.
Yu YE, Zhang Y, Unni E, et al. (2000). "Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice". Proc. Natl. Acad. Sci. U.S.A. 97 (9): 4683–8. doi:10.1073/pnas.97.9.4683. PMC 18293. PMID 10781074.
Siffroi JP, Alfonsi MF, Dadoune JP (2001). "Electron microscopic in situ hybridization study of simultaneous expression of TNP1 and PRM1 genes in human spermatids". Italian Journal of Anatomy and Embryology = Archivio Italiano di Anatomia ed Embriologia. 103 (4 Suppl 1): 65–74. PMID 11315969.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Miyagawa Y, Nishimura H, Tsujimura A, et al. (2006). "Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations". J. Androl. 26 (6): 779–86. doi:10.2164/jandrol.05069. PMID 16291974.
Jedrzejczak P, Kempisty B, Bryja A, et al. (2007). "Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men". Arch. Androl. 53 (4): 199–205. doi:10.1080/01485010701426430. PMID 17852044. S2CID 21999596.

인간 염색체 2의 유전자에 관한 이 기사는 단조롭다.위키피디아를 확장하여 도울 수 있다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리스 89: ENSG00000118245 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리스 89: ENSMUSG000026182 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2249851-5] Luerssen H, Mattei MG, Schroter M, Grzeschik KH, Adham IM, Engel W (Jan 1991). "Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2". Genomics. 8 (2): 324–30. doi:10.1016/0888-7543(90)90289-7. PMID 2249851.

[entrez-6] "Entrez Gene: TNP1 transition protein 1 (during histone to protamine replacement)".

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