CYP53 패밀리
CYP53 familyCYP53으로도 알려진 시토크롬 P450 패밀리 53은 탄화수소 [1]동화와 관련된 균류의 시토크롬 P450 모노옥시게나아제 패밀리이다.그것들은 아스코마이코타와 담자균코타 둘 다에 분포하고 있으며, 항진균제 [2]표적으로 사용될 수 있다.벤조산염 4-모노옥시게나아제(bphA)[3]를 코드하는 아스페르길루스 니제르(Aspergillus niger)의 CYP53A1이다.
레퍼런스
- ^ Huarte-Bonnet C, Kumar S, Saparrat MC, Girotti JR, Santana M, Hallsworth JE, Pedrini N (March 2018). "Insights into Hydrocarbon Assimilation by Eurotialean and Hypocrealean Fungi: Roles for CYP52 and CYP53 Clans of Cytochrome P450 Genes". Applied Biochemistry and Biotechnology. 184 (3): 1047–1060. doi:10.1007/s12010-017-2608-z. PMID 28942502. S2CID 3500301.
- ^ Jawallapersand P, Mashele SS, Kovačič L, Stojan J, Komel R, Pakala SB, et al. (2014). "Cytochrome P450 monooxygenase CYP53 family in fungi: comparative structural and evolutionary analysis and its role as a common alternative anti-fungal drug target". PLOS ONE. 9 (9): e107209. Bibcode:2014PLoSO...9j7209J. doi:10.1371/journal.pone.0107209. PMC 4164535. PMID 25222113. S2CID 11892176.
- ^ Faber BW, van Gorcom RF, Duine JA (October 2001). "Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger". Archives of Biochemistry and Biophysics. 394 (2): 245–54. doi:10.1006/abbi.2001.2534. PMID 11594739.