뉴로메딘 S

Neuromedin S
뉴로메딘 S
식별자
기호.NMS
NCBI유전자129521
HGNC32203
기타 데이터
궤적제2장 문제 11.2

뉴로메딘 S는 인간과 다른 포유류의 뇌에서 발견되는 36-아미노산 신경펩타이드이다.시상 하부의suprachiasmatic 핵으로 관련된다 뉴로메 딘 U. 그것은 생각해 있다에 관련된 규제의 24시간 주기 리듬과는 또한 appetite 억제제 effects,[1][2][3][4][5]뿐만 아니라 규제 해제의 다른 몇몇 펩티드 호르몬과 같vasopressin,[6]황체 형성 hormone,[7]과 옥시토신.[8]

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레퍼런스

  1. ^ Mori K, Miyazato M, Ida T, Murakami N, Serino R, Ueta Y, Kojima M, Kangawa K (January 2005). "Identification of neuromedin S and its possible role in the mammalian circadian oscillator system". The EMBO Journal. 24 (2): 325–35. doi:10.1038/sj.emboj.7600526. PMC 545815. PMID 15635449.
  2. ^ Mori K, Miyazato M, Kangawa K (2008). "Neuromedin S: discovery and functions". Results and Problems in Cell Differentiation. 46: 201–12. doi:10.1007/400_2007_054. ISBN 978-3-540-78350-3. PMID 18214396.
  3. ^ Novak CM (July 2009). "Neuromedin S and U". Endocrinology. 150 (7): 2985–7. doi:10.1210/en.2009-0448. PMC 2703548. PMID 19549882.
  4. ^ Peier A, Kosinski J, Cox-York K, Qian Y, Desai K, Feng Y, Trivedi P, Hastings N, Marsh DJ (July 2009). "The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2)". Endocrinology. 150 (7): 3101–9. doi:10.1210/en.2008-1772. PMC 2703546. PMID 19324999.
  5. ^ Mitchell J, Maguire J, Davenport A (June 2009). "Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S". British Journal of Pharmacology. 158 (1): 87–103. doi:10.1111/j.1476-5381.2009.00252.x. PMC 2795236. PMID 19519756.
  6. ^ Sakamoto T, Mori K, Nakahara K, Miyazato M, Kangawa K, Sameshima H, Murakami N (September 2007). "Neuromedin S exerts an antidiuretic action in rats". Biochemical and Biophysical Research Communications. 361 (2): 457–61. doi:10.1016/j.bbrc.2007.07.036. PMID 17645872.
  7. ^ Vigo E, Roa J, López M, Castellano JM, Fernandez-Fernandez R, Navarro VM, Pineda R, Aguilar E, Diéguez C, Pinilla L, Tena-Sempere M (February 2007). "Neuromedin s as novel putative regulator of luteinizing hormone secretion". Endocrinology. 148 (2): 813–23. doi:10.1210/en.2006-0636. PMID 17110433.
  8. ^ Sakamoto T, Mori K, Miyazato M, Kangawa K, Sameshima H, Nakahara K, Murakami N (October 2008). "Involvement of neuromedin S in the oxytocin release response to suckling stimulus". Biochemical and Biophysical Research Communications. 375 (1): 49–53. doi:10.1016/j.bbrc.2008.07.124. PMID 18675786.