55kDa의 센트로솜 단백질 은 CEP55 [5] [6] 단백질 이다.
CEP55는 세포 [7] cytokinesis )에 중요한 역할을 하는 유사분열성 인단백질 이다. 신경줄기세포에 [8] 섬모세포 가 형성됩니다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000138180 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000024989 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, Khanna KK (Oct 2005). "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis" . Dev Cell . 9 (4): 477–88. doi :10.1016/j.devcel.2005.09.003 PMID 16198290 . ^ "Entrez Gene: CEP55 centrosomal protein 55kDa" .^ van der Horst A, Simmons J, Khanna KK (November 2009). "Cep55 stabilization is required for normal execution of cytokinesis" . Cell Cycle . 8 (22): 3742–9. doi :10.4161/cc.8.22.10047 PMID 19855176 . ^ Behnam Rashidieh,Belal Shohayeb,Amanda Louise Bain,Patrick R. J. Fortuna,Debottam Sinha,Andrew Burgess,Richard Mills,Rachael C. Adams,J. Alejandro Lopez,Peter Blumbergs,John Finnie,Murugan Kalimutho,Michael Piper,James Edward Hudson,Dominic C. H. Ng ,Kum Kum Khanna. (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis" . PLoS Genetics . doi :10.1371/journal.pgen.1009334 PMID 34710087 . {{cite journal }}: CS1 maint: 작성자 파라미터 사용(링크 ) 외부 링크 추가 정보 Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10" . Nature . 429 (6990): 375–81. doi :10.1038/nature02462 PMID 15164054 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Martinez-Garay I, Rustom A, Gerdes HH, Kutsche K (2006). "The novel centrosomal associated protein CEP55 is present in the spindle midzone and the midbody" . Genomics . 87 (2): 243–53. doi :10.1016/j.ygeno.2005.11.006 PMID 16406728 . Zhao WM, Seki A, Fang G (2006). "Cep55, a Microtubule-bundling Protein, Associates with Centralspindlin to Control the Midbody Integrity and Cell Abscission during Cytokinesis" . Mol. Biol. Cell . 17 (9): 3881–96. doi :10.1091/mbc.E06-01-0015 . PMC 1593165 PMID 16790497 . Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Chen CH, Lu PJ, Chen YC, et al. (2007). "FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway" . Oncogene . 26 (29): 4272–83. doi :10.1038/sj.onc.1210207 PMID 17237822 . Carlton JG, Martin-Serrano J (2007). "Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery" . Science . 316 (5833): 1908–12. doi :10.1126/science.1143422 . PMID 17556548 . S2CID 29191843 . Morita E, Sandrin V, Chung HY, et al. (2007). "Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis" . EMBO J . 26 (19): 4215–27. doi :10.1038/sj.emboj.7601850 . PMC 2230844 PMID 17853893 .
