톨로이드상 단백질 1은 TLL1 [5] [6] 단백질 이다.
이 유전자는 아스타신 유사 아연 의존성 금속단백질가수분해효소를 코드하고 메츠신시 계열의 아족이다. 생쥐의 유사한 단백질은 심장 발달 중에 필요하며,[6] 코딘 을 처리 한다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG000038295 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000053626 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Scott IC, Clark TG, Takahara K, Hoffman GG, Eddy RL, Haley LL, Shows TB, Greenspan DS (Oct 1999). "Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32→q33 and 10q23→q24 and assignment of murine Tll2 to chromosome 19". Cytogenet Cell Genet . 86 (1): 64–5. doi :10.1159/000015412 . PMID 10516436 . S2CID 42081614 . ^ a b "Entrez Gene: TLL1 tolloid-like 1" . 추가 정보 Takahara K, Brevard R, Hoffman GG, et al. (1997). "Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1". Genomics . 34 (2): 157–65. doi :10.1006/geno.1996.0260 . PMID 8661043 . Scott IC, Blitz IL, Pappano WN, et al. (1999). "Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis" . Dev. Biol . 213 (2): 283–300. doi :10.1006/dbio.1999.9383 PMID 10479448 . Scott IC, Imamura Y, Pappano WN, et al. (2000). "Bone morphogenetic protein-1 processes probiglycan" . J. Biol. Chem . 275 (39): 30504–11. doi :10.1074/jbc.M004846200 PMID 10896944 . Uzel MI, Scott IC, Babakhanlou-Chase H, et al. (2001). "Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures" . J. Biol. Chem . 276 (25): 22537–43. doi :10.1074/jbc.M102352200 PMID 11313359 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Ge G, Zhang Y, Steiglitz BM, Greenspan DS (2006). "Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains" . J. Biol. Chem . 281 (16): 10786–98. doi :10.1074/jbc.M511111200 PMID 16507574 .
