히스타틴 1

HTN1
식별자
에일리어스	HTN1, HIS1, 히스타틴1
외부 ID	OMIM: 142701 HomoloGene: 88658 GenCard: HTN1
유전자 위치(인간)
크르.	4번 염색체(인간)
끝.	70,058,848 bp
RNA발현패턴
	상단 표시 위치:
	침샘; ; 소침샘; ; 태반; ; 흉선; ; 골수; ; 골격근 조직; ; 방광; ; 단구; ; 전전두피질; ; 췌장;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	GO:0001948 단백질 결합;
셀룰러 컴포넌트	세포외 영역; 세포외 공간;
생물학적 과정	생체 조직 발달; 세균에 대한 방어 반응; 곰팡이에 대한 방어 반응; 항균성 체액 반응; 다른 유기체의 세포 사멸;
	출처:아미고 / QuickGO
맞춤법
	3346
	없음
	ENSG00000283046; ENSG00000126550
	없음
	P15515
	없음
	NM_002159; NM_001368990
	없음
	NP_002150; NP_001355919
	없음
	위키데이터
인간 보기/편집

히스타틴-1은 인간에서 HTN1 유전자에 ^[3]의해 암호화되는 단백질이다.

레퍼런스

^ ^a ^b ^c ENSG00000126550 GRCh38: 앙상블 릴리즈 89: ENSG00000283046, ENSG00000126550 - Ensembl, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HTN1 histatin 1".

추가 정보

Sugiyama K, Ogino T, Ogata K (1990). "Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva". Arch. Oral Biol. 35 (6): 415–9. doi:10.1016/0003-9969(90)90202-L. PMID 2372245.
Sabatini LM, Azen EA (1989). "Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2)". Biochem. Biophys. Res. Commun. 160 (2): 495–502. doi:10.1016/0006-291X(89)92460-1. PMID 2719677.
vanderSpek JC, Wyandt HE, Skare JC, et al. (1989). "Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs". Am. J. Hum. Genet. 45 (3): 381–7. PMC 1683406. PMID 2773933.
Oppenheim FG, Xu T, McMillian FM, et al. (1988). "Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans". J. Biol. Chem. 263 (16): 7472–7. doi:10.1016/S0021-9258(18)68522-9. PMID 3286634.
Oppenheim FG, Yang YC, Diamond RD, et al. (1986). "The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion". J. Biol. Chem. 261 (3): 1177–82. doi:10.1016/S0021-9258(17)36072-6. PMID 3944083.
Sabatini LM, Ota T, Azen EA (1993). "Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family". Mol. Biol. Evol. 10 (3): 497–511. doi:10.1093/oxfordjournals.molbev.a040022. PMID 8336540.
Driscoll J, Zuo Y, Xu T, et al. (1996). "Functional comparison of native and recombinant human salivary histatin 1". J. Dent. Res. 74 (12): 1837–44. CiteSeerX 10.1.1.532.5059. doi:10.1177/00220345950740120601. PMID 8600179. S2CID 38609550.
Iontcheva I, Oppenheim FG, Offner GD, Troxler RF (2000). "Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid system". J. Dent. Res. 79 (2): 732–9. doi:10.1177/00220345000790020601. PMID 10728974. S2CID 27558675.
Flora B, Gusman H, Helmerhorst EJ, et al. (2002). "A new method for the isolation of histatins 1, 3, and 5 from parotid secretion using zinc precipitation". Protein Expr. Purif. 23 (1): 198–206. doi:10.1006/prep.2001.1493. PMID 11570863.
Tamaki N, Tada T, Morita M, Watanabe T (2003). "Comparison of inhibitory activity on calcium phosphate precipitation by acidic proline-rich proteins, statherin, and histatin-1". Calcif. Tissue Int. 71 (1): 59–62. doi:10.1007/s00223-001-1084-0. PMID 12060866. S2CID 38221230.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yin A, Margolis HC, Grogan J, et al. (2003). "Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins". Arch. Oral Biol. 48 (5): 361–8. doi:10.1016/S0003-9969(03)00012-8. PMID 12711380.
Michels AA, Nguyen VT, Fraldi A, et al. (2003). "MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner". Mol. Cell. Biol. 23 (14): 4859–69. doi:10.1128/MCB.23.14.4859-4869.2003. PMC 162212. PMID 12832472.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Bruno LS, Li X, Wang L, et al. (2005). "Two-hybrid analysis of human salivary mucin MUC7 interactions". Biochim. Biophys. Acta. 1746 (1): 65–72. doi:10.1016/j.bbamcr.2005.08.007. PMID 16203048.
Cabras T, Fanali C, Monteiro JA, et al. (2007). "Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland". J. Proteome Res. 6 (7): 2472–80. doi:10.1021/pr0700706. PMID 17503797.

인간 염색체 4번 유전자에 대한 이 기사는 짧은 글이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] ENSG00000126550 GRCh38: 앙상블 릴리즈 89: ENSG00000283046, ENSG00000126550 - Ensembl, 2017년 5월

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: HTN1 histatin 1".

[1]

[2]

[3]

v t 모공형성독소(TC 1C)
항균성 양이온성 펩타이드	카테리시딘 데펜신 더미시딘 히스타틴(HTN1, HTN3)
기타, 인간	천공
기타, 비인간	세크로핀 디프테리아 독소 더마셉틴 라타르신 마자이닌 메리틴 니신 기모신

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