복제인자 C 서브유닛3 은 RFC3 [5] [6] 단백질 이다.
기능. DNA 중합효소 델타 및 DNA 중합효소 엡실론 에 의한 프라이밍 DNA 템플릿의 연장은 세포핵항원(PCNA )과 복제인자 C(RFC)를 증식시키는 보조단백질을 필요로 한다. RFC(액티베이터 1이라고도 함)는 140, 40, 38, 37 및 36kDa의 5개의 서로 다른 서브유닛으로 이루어진 단백질 복합체입니다. 이 유전자는 38kDa 서브유닛을 암호화한다. 이 서브유닛은 140kDa 서브유닛과 36, 37, 40kDa 서브유닛으로 구성된 코어복합체 사이의 상호작용에 필수적이다. 서로 다른 Isoforms를 코드하는 대체 스플라이스된 전사 변종이 [6]
상호 작용 RFC3은 다음 제품과 상호 작용하는 것 으로 나타났습니다.
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