스트린

스트린
식별자
에일리어스	STRN, SG2NA, PPP2R6A, 스트리틴, STRN1
외부 ID	OMIM : 614765 MGI : 1333757 HomoloGene : 2380 Gene Card : STRN
유전자 위치(인간)
크르.	2번 염색체(인간)
끝.	36,966,536 bp
유전자 위치(마우스)
크르.	17번 염색체(쥐)
끝.	79,044,625 bp
RNA발현패턴
	상단 표시 위치:
	내피 세포; ; 양수; ; 뇌량; ; 아킬레스건; ; 구강; ; 미주신경의 하부 신경절; ; 생식 상피; ; 시상하핵; ; 브로드만 23구역; ; 두정 흉막;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	단백질인산가수분해효소2A결합; 에스트로겐수용체결합; GO:0001948 단백질 결합; 칼모듈린 결합; 아르마딜로 반복 도메인 결합; GO:0032403 단백질 함유 복합결합;
셀룰러 컴포넌트	세포질; 신경세포체; 시냅스 후막; 수상척추; 단백질인산가수분해효소2A복합체; 세포 투영; 막; GO:0097483, GO:0097481 시냅스 후 밀도; 이세포밀접합; 수상돌기; FAR/SIN/STRIPAK 복합체;
생물학적 과정	수상돌기의 발달; Wnt 시그널링 패스; 운동 거동; 세포군 증식의 음성 조절; 이세포밀접합체;
	출처:아미고 / QuickGO
맞춤법
	6801
	268980
	ENSG00000115808
	ENSMUSG000024077
	O43815
	O55106
	NM_003162
	NM_011500
	NP_003153
	NP_035630
	위키데이터
인간 보기/편집	마우스 표시/편집

스트리틴은 STRN ^[5]^[6]^[7]유전자에 의해 인간에게 암호화되는 단백질이다.

상호 작용

STRN은 다음과 상호작용하는 것으로 나타났습니다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000115808 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000024077 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Moqrich A, Mattei MG, Bartoli M, Rakitina T, Baillat G, Monneron A, Castets F (Jul 1998). "Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain". Genomics. 51 (1): 136–9. doi:10.1006/geno.1998.5342. PMID 9693043.
^ Castets F, Bartoli M, Barnier JV, Baillat G, Salin P, Moqrich A, Bourgeois JP, Denizot F, Rougon G, Calothy G, Monneron A (Aug 1996). "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons". The Journal of Cell Biology. 134 (4): 1051–62. doi:10.1083/jcb.134.4.1051. PMC 2120968. PMID 8769426.
^ "Entrez Gene: STRN striatin, calmodulin binding protein".
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.
^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

추가 정보

Moreno CS, Park S, Nelson K, Ashby D, Hubalek F, Lane WS, Pallas DC (Feb 2000). "WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A". The Journal of Biological Chemistry. 275 (8): 5257–63. doi:10.1074/jbc.275.8.5257. PMC 3505218. PMID 10681496.
Gaillard S, Bartoli M, Castets F, Monneron A (Nov 2001). "Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1". FEBS Letters. 508 (1): 49–52. doi:10.1016/S0014-5793(01)03020-4. PMID 11707266. S2CID 7887096.
Huang Y, Tang R, Dai J, Gu S, Zhao W, Cheng C, Xu M, Zhou Z, Ying K, Xi Y, Mao Y (2002). "A novel human hydroxysteroid dehydrogenase like 1 gene (HSDL1) is highly expressed in reproductive tissues". Molecular Biology Reports. 28 (4): 185–91. doi:10.1023/A:1015726217890. PMID 12153137. S2CID 9167130.
Hwang J, Pallas DC (February 2014). "STRIPAK complexes: structure, biological function, and involvement in human diseases". The International Journal of Biochemistry & Cell Biology. 47: 118–48. doi:10.1016/j.biocel.2013.11.021. PMC 3927685. PMID 24333164.
Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (Jul 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH (Dec 2004). "Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha". Proceedings of the National Academy of Sciences of the United States of America. 101 (49): 17126–31. doi:10.1073/pnas.0407492101. PMC 534607. PMID 15569929.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

인간 염색체 2번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000115808 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000024077 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9693043-5] Moqrich A, Mattei MG, Bartoli M, Rakitina T, Baillat G, Monneron A, Castets F (Jul 1998). "Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain". Genomics. 51 (1): 136–9. doi:10.1006/geno.1998.5342. PMID 9693043.

[pmid8769426-6] Castets F, Bartoli M, Barnier JV, Baillat G, Salin P, Moqrich A, Bourgeois JP, Denizot F, Rougon G, Calothy G, Monneron A (Aug 1996). "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons". The Journal of Cell Biology. 134 (4): 1051–62. doi:10.1083/jcb.134.4.1051. PMC 2120968. PMID 8769426.

[entrez-7] "Entrez Gene: STRN striatin, calmodulin binding protein".

[pmid18782753-8] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

[pmid17353931-9] Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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스트린

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