호모 사피엔스 종의 단백질 코드 유전자
셉틴12 는 사람에게서 셉틴12 [5] 단백질 이다.
기능. 이 유전자는 구아닌-뉴클레오티드 결합 단백질과 세포골격계 GTPase 의 셉틴 계열의 멤버를 암호화한다. 셉틴은 사이토카인시스 , 세포외전증 , 배아발달, 막역학에 중요한 역할을 한다. 이 [5]
레퍼런스 추가 정보 Kuo PL, Chiang HS, Wang YY, Kuo YC, Chen MF, Yu IS, Teng YN, Lin SW, Lin YH (2013). "SEPT12-microtubule complexes are required for sperm head and tail formation" . International Journal of Molecular Sciences . 14 (11): 22102–16. doi :10.3390/ijms141122102 PMC 3856054 PMID 24213608 . Hall PA, Jung K, Hillan KJ, Russell SE (July 2005). "Expression profiling the human septin gene family". The Journal of Pathology . 206 (3): 269–78. doi :10.1002/path.1789 . PMID 15915442 . S2CID 42206750 . Kinoshita M (2003). "The septins" . Genome Biology . 4 (11): 236. doi :10.1186/gb-2003-4-11-236 . PMC 329110 PMID 14611653 . Ding X, Yu W, Liu M, Shen S, Chen F, Wan B, Yu L (November 2007). "SEPT12 interacts with SEPT6 and this interaction alters the filament structure of SEPT6 in Hela cells" . Journal of Biochemistry and Molecular Biology . 40 (6): 973–8. doi :10.5483/bmbrep.2007.40.6.973 PMID 18047794 . Kuo YC, Lin YH, Chen HI, Wang YY, Chiou YW, Lin HH, Pan HA, Wu CM, Su SM, Hsu CC, Kuo PL (April 2012). "SEPT12 mutations cause male infertility with defective sperm annulus" . Human Mutation . 33 (4): 710–9. doi :10.1002/humu.22028 PMID 22275165 . S2CID 7923473 . Miyakawa H, Miyamoto T, Koh E, Tsujimura A, Miyagawa Y, Saijo Y, Namiki M, Sengoku K (2012). "Single-nucleotide polymorphisms in the SEPTIN12 gene may be a genetic risk factor for Japanese patients with Sertoli cell-only syndrome" . Journal of Andrology . 33 (3): 483–7. doi :10.2164/jandrol.110.012146 PMID 21636737 . Lin YH, Wang YY, Chen HI, Kuo YC, Chiou YW, Lin HH, Wu CM, Hsu CC, Chiang HS, Kuo PL (2012). "SEPTIN12 genetic variants confer susceptibility to teratozoospermia" . PLOS ONE . 7 (3): e34011. Bibcode :2012PLoSO...734011L . doi :10.1371/journal.pone.0034011 PMC 3316533 PMID 22479503 . Lin YH, Lin YM, Wang YY, Yu IS, Lin YW, Wang YH, Wu CM, Pan HA, Chao SC, Yen PH, Lin SW, Kuo PL (May 2009). "The expression level of septin12 is critical for spermiogenesis" . The American Journal of Pathology . 174 (5): 1857–68. doi :10.2353/ajpath.2009.080955 . PMC 2671274 PMID 19359518 . Miyamoto T, Tsujimura A, Miyagawa Y, Koh E, Namiki M, Horikawa M, Saijo Y, Sengoku K (January 2012). "Single nucleotide polymorphisms in the SEPTIN12 gene may be associated with azoospermia by meiotic arrest in Japanese men" . Journal of Assisted Reproduction and Genetics . 29 (1): 47–51. doi :10.1007/s10815-011-9679-5 . PMC 3252415 PMID 22116646 . 외부 링크 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
