호모 사피엔스 종의 단백질 코드 유전자
페르옥시좀막단백질 PEX14는 PEX14 유전자에 [5] [6] 단백질 이다.
기능. 이 유전자는 과산화염색체 수입기구의 필수 성분을 암호화한다. 단백질은 C 말단이 세포에 노출되어 있는 과산화소체 막에 통합되어 PTS1 과산화소체 표적화 신호를 포함하는 단백질에 대해 세포질 수용체와 상호작용한다. 단백질은 또한 전사 코어프레서로서 기능하며 히스톤탈아세틸라아제와 상호작용한다. 이 유전자의 돌연변이는 젤위거 [6]
상호 작용 PEX14는 다음과 같이 동작하고 있습니다 .
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000142655 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000028975 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Fransen M, Terlecky SR, Subramani S (Jul 1998). "Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import" . Proceedings of the National Academy of Sciences of the United States of America . 95 (14): 8087–92. doi :10.1073/pnas.95.14.8087 PMC 20933 PMID 9653144 . ^ a b "Entrez Gene: PEX14 peroxisomal biogenesis factor 14" .^ a b Otera H, Setoguchi K, Hamasaki M, Kumashiro T, Shimizu N, Fujiki Y (Mar 2002). 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