보존된 과점골지 복합소단위 7 은 인간에서 COG7 유전자 에 의해 암호화된 단백질 이다.[5] [6]
다단백질 복합체는 골기 기구 구조와 세포내 수송 및 당단백질 수정의 핵심 결정 요인이다. 골지교통단지 (GTC)와 글리코실화반응을 일으키는 LDLC단지, 배실류 수송에 관여하는 SEC34단지 등 여러 단지가 확인됐다.이들 3개 단지는 동일하며 COG7(Ungar et al., 2002)이 포함된 보존과점골지( COG) 복합단지 로 불렸다. [OMIM에 의해 제공][6]
상호작용 COG7은 COG4 [7] COG5 와 상호작용 하는 것으로 나타났다.[7]
참조 ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000168434 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000034951 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function" . J Cell Biol . 157 (3): 405–15. doi :10.1083/jcb.200202016 . PMC 2173297 PMID 11980916 . ^ a b "Entrez Gene: COG7 component of oligomeric golgi complex 7" .^ a b Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex" . J. Biol. Chem . 279 (23): 24640–8. doi :10.1074/jbc.M400662200 ISSN 0021-9258 . PMID 15047703 .
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