트랜스막 BAX 억제제 모티브 함유 단백질 4는 TMBM4 [5] [6] [7] 단백질 이다.그것은 그 기능과 세포하 국재성 때문에 인간 골지 항아포토시스 단백질( hGAAP) 로도 알려져 있다.
기능. Human GAAP은 Golgi 에 존재하는 단백질로 프로그램된 세포사멸의 한 형태인 아포토시스 를 조절하는 데 도움을 줍니다. Ca의 플럭스를 규제함 으로써+2 GAAP의 증가는 아포토시스 [9] [10] GAAP은 또한 세포[11] [13] 기타 GAAP은 분석된 모든 Eucaryotes 및 일부 박테리아에서 찾을 수 있습니다. 바이러스 GAAP(vGAAP)는 천연두 박멸에 사용되는 살아있는 백신인 바시니아 바이러스의 일부 변종에서도 발견될 수 있습니다.
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